Results 81 to 90 of about 190,703 (303)
Blockage fuel pin simulator experiments and simulation
, 2019 This work reports the experimental results and post-test analysis carried out in the heavy liquid metal-operated NACIE-UP facility in the framework of the HORIZON2020 SESAME project. NACIE-UP is a rectangular loop,where the two vertical pipes, which work
Di Piazza I. +3 more
core +1 more source
Limited by Capacity or Blockage? A Millimeter Wave Blockage Analysis
, 2018 Millimeter wave (mmWave) communication systems can provide high data rates but the system performance may degrade significantly due to mobile blockers and the user's own body. A high frequency of interruptions and long duration of blockage may degrade the quality of experience.
Jain, Ish Kumar +2 more
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ore pass level and blockage locator device [PDF]
"Bridging of material in ore passes causes blockages in the flow of material. These blockages can be hazardous and must be removed before production can continue.
core +2 more sources
Laparoscopic Correction of Cesarean Scar Defects by Temporary Bilateral Uterine Artery Occlusion
Clinical and Experimental Obstetrics & GynecologyBackground: The aim of our study was to evaluate the clinical efficacy of temporary bilateral uterine artery blockage for cesarean scar defects when combined with laparoscopy and hysteroscopy.
Fei Tang +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
IEEE AccessBlockage of propagation paths between the base station (BS) and user equipment (UE), as well as the micromobility of the UE, are known to be critical phenomena affecting the performance of 6G subterahertz/terahertz (sub-THz/THz, 0.1–0.3/0.3–
Vitalii Beschastnyi +7 more
doaj +1 more source