Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Flow and Pressure Characteristics Downstream of a Segmental Blockage in a Turbulent Pipe Flow
, 1979 Two mutually complementary sets of experiments were performed to study the flow and pressure fields created by the presence of a segmental orifice plate in a circular tube.
J. W. Ramsey, S. C. Lau, E. M. Sparrow
core +1 more source
Modelling blockage effects using a spectral element method [PDF]
, 2005 We employ a two-dimensional spectral element method to investigate the effect of various semi-circular blockages on the laminar flow between two flat plates.
Hourigan, K. +2 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Actuator Blockage Detection in Milligravity [PDF]
Exploration rover like IDEFIX, the rover of the Martian Moons Exploration Mission (MMX), even when designed with extraordinary diligence, can get stuck in their environment or be affected by other faults.
Holderried, Roman +2 more
core +1 more source
Study on the Arching Shaping and Blockage Mechanism during Silo Discharge Process
Liang you shipin ke-jiIn granular material conveying systems, the smoothness of the unloading process is directly related to operational efficiency. When the ratio of the size of the granular material in the silo to the size of the discharge port is within a specific range ...
LIU Ke-jin +4 more
doaj +1 more source
Multi-Band Vehicle-to-Vehicle Channel Characterization in the Presence of Vehicle Blockage
IEEE Access, 2019 Vehicle-to-vehicle (V2V) channels exhibit unique properties due to the highly dynamic environment and low elevation of the antennas at both ends of the link.
Mate Boban +10 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Blockage at cross-drainage hydraulic structures – Advances, challenges and opportunities
Blockage of cross-drainage hydraulic structures is a significant concern in water resources and civil engineering projects, particularly in urban areas experiencing increased debris supply.
Muhammad Zain Bin Riaz, Umair Iqbal
core +1 more source
Coverage, Capacity, and Error Rate Analysis of Multi-Hop Millimeter-Wave Decode and Forward Relaying
IEEE Access, 2019 In this paper, we analyze the end-to-end (e2e) performance of a millimeter-wave (mmWave) multi-hop relay network. The relays in it are decode-and-forward (DF) type.
Khagendra Belbase +2 more
doaj +1 more source