Results 161 to 170 of about 194,544 (300)

Sustainability-aware user association for RIS-assisted mmWave networks in dense blockage environment. [PDF]

PLoS One
Mumtaz A, Ali S, Aslam MI.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Sub-Nanomolar Detection and Discrimination of Microcystin Congeners Using Aerolysin Nanopores. [PDF]

ACS Nano
Agerova A, Bada Juarez JF, Perrin LW, Abriata LA, Marcaida MJ, Carratalà A, Selmani N, Barbier S, Khajehnouri F, Vassalli G, Janssen EML, Cao C, Kohn T, Dal Peraro M.   +13 more
europepmc   +1 more source

Partial Blockage [PDF]

, 2020
openaire   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Introducing the Quality Target Administration (QTAP) Profile for Enteral Feeding Tube Medications. [PDF]

Pharmaceutics
Salunke S, Chan CKA, Hu S.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Probing Voltage Dependence Interaction of Cationic Peptides with Bacterial Porins at A Single-Molecule Level. [PDF]

Cell Biochem Biophys
Prasad S.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Modeling blockage in high directional wireless. systems

While the wireless word moves towards higher frequency bands, new challenges arises, due to the inherent characteristics of the transmission links, such as high path and penetration losses.
Koutsonas, Evangelos, Boulogeorgos, Alexandros-Apostolos A., Trevlakis, Stylianos E., Tsiftis, Theodoros A., Ali, Tanweer   +4 more
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