Results 151 to 160 of about 190,703 (303)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effect of Electrolyte, Applied Voltage, and DNA Concentration on the Translocation Dynamics of a Single-Stranded DNA through a Solid-State Nanopore. [PDF]

ACS Omega
Zerolová A, Mondal S, Piskunen P, Kostiainen MA, Linko V.   +4 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Sustainability-aware user association for RIS-assisted mmWave networks in dense blockage environment. [PDF]

PLoS One
Mumtaz A, Ali S, Aslam MI.
europepmc   +1 more source

Uterine artery blockage

Taiwanese Journal of Obstetrics and Gynecology
I-Gung Li, Hung-Hsien Liu, Peng-Hui Wang
openaire   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Editorial: From micro to macro: interactions of marine biota with plastic pollution

Frontiers in Marine Science
Sonja M. Ehlers, Julius A. Ellrich, Felix Weber   +2 more
doaj   +1 more source

Sub-Nanomolar Detection and Discrimination of Microcystin Congeners Using Aerolysin Nanopores. [PDF]

ACS Nano
Agerova A, Bada Juarez JF, Perrin LW, Abriata LA, Marcaida MJ, Carratalà A, Selmani N, Barbier S, Khajehnouri F, Vassalli G, Janssen EML, Cao C, Kohn T, Dal Peraro M.   +13 more
europepmc   +1 more source

Bureaucratic Blockages

, 2017
How do civil servants in district water and sanitation departments address problems of water access in rural communities in Tanzania? What are the bureaucratic procedures they follow? How do the bureaucratic procedures around formulating budgets, managing money, and interacting with communities impede or enhance their ability to manage water projects ...
openaire   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source