Results 61 to 70 of about 1,033,682 (248)

La langue francaise dans les disciplines non linguistiques: facteur de réussite ou de d’inhibition ? [PDF]

Studii si Cercetari Filologice: Seria Limbi Straine Aplicate, 2018
The French language, the first living language in a school system in great difficulty, has gone from the status of a "second language" to a "foreign language"; it is for this reason that it is laborious to determine the real status of this language in ...
Moulay Mohamed Tarnaoui
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The Estimation Distribution Algorithm for the Blocking Job Shop Scheduling Problem

Applied Sciences
The blocking job shop problem (BJSSP) is a variant of the classical job shop problem, where a job completed on one machine cannot be transferred to the next machine until the latter becomes available, causing the current machine to remain blocked.
John Valencia, Elkin Rodríguez-Velásquez   +1 more
doaj   +1 more source

The Dynamic Character of Northern Hemisphere Flow Regimes in a Near-Term Climate Change Projection

Atmosphere, 2018
The dynamic character of an enstrophy-based diagnostic, previously used in the study of atmospheric blocking, is examined here, in near-term future simulations from the Institut Pierre Simon Laplace Climate Model version 4 (IPSL-CM4) and version 5 (IPSL ...
Andrew D. Jensen, Mirseid G. Akperov, Igor I. Mokhov, Anthony R. Lupo, Fengpeng Sun   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Numerical simulations of sand‐screen performance in unconsolidated prepacked gravel screen

Energy Science & Engineering
This work addresses the ongoing challenge of optimizing sand control screens, attributed to a limited understanding of screen blocking. A novel one‐way computational fluid dynamics and discrete element method (CFD–DEM) coupling technique is presented to ...
Chengyun Ma, Yihua Dou, Jingen Deng, Cheng Hui, Kai Zhao, Yongcun Feng, Liangbin Dou   +6 more
doaj   +1 more source

Improving Petrophysical Interpretation of Conventional Log ‎by Determination of Real Bed Boundaries [PDF]

Journal of Sciences, Islamic Republic of Iran, 2017
Proper determination of bed boundaries in layered reservoirs is vital ‎for accurate petrophysical interpretation of conventional logs. In the ‎wellbore, logs continuously measure physical properties of reservoir ‎while the properties change stepwise ...
F. Khoshbakht, M. R. Rasaie, A. Shekarifard   +2 more
doaj  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Experimental Research and Development of Nonlinearity Models for FR1 Range Mixers for Electromagnetic Compatibility Analysis

Доклады Белорусского государственного университета информатики и радиоэлектроники
By using the technology of double-frequency testing, an experimental analysis of nonlinear properties of low-power radio-frequency mixers is performed at frequencies of the n7 band allocated in Belarus for 4G mobile communication systems and the n78 band
E. V. Sinkevich, V. I. Mordachev, Wan Fayu, D. A. Tsyanenka, I. V. Shakinka   +4 more
doaj   +1 more source