Results 41 to 50 of about 21,280 (301)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Content Delivery From the Sky: Drone-Aided Load Balancing for Mobile-CDN
EAI Endorsed Transactions on Industrial Networks and Intelligent Systems, 2022 The Base Station based Mobile-CDN architecture redirects the content request of mobile users to other base stations during storage misses. These request redirections increase the latency of a mobile client through unbalanced load distributions among ...
T. Bilen, B. Canberk
doaj +1 more source
Blocking probability in a caching hierarchy network
2011 IEEE Consumer Communications and Networking Conference (CCNC), 2011 We develop a performance model for the availability of a MobileTV service in a caching hierarchy network. The probability that bandwidth for the service is available is calculated as a function of channel popularity, the number of available channels, cache sizes, network configuration, and content viewing behavior.
Yue Lu 0006 +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Exact calculation of blocking probabilities for bufferless optical burst switched links with partial wavelength conversion [PDF]
, 2004 Date of Conference: 25-29 Oct. 2004Conference name: First International Conference on Broadband Networks, 2004In this paper, we study the blocking probabilities in a wavelength division multiplexing-based asynchronous bufferless optical burst switch ...
Akar, Nail, Karasan, Ezhan
core +1 more source
Blocking probability analysis of wireless sensors that employ opportunistic spectrum access
JOIV: International Journal on Informatics Visualization, 2017 Opportunistic accessing of vacant channels of licensed spectrum by non-licensed wireless devices offers a convenient solution to the spectrum scarcity problems experienced by many wireless communication systems.
Lingineni Anusha, B Seetha ramanjaneyulu
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
AN EFFECTIVE ROUTING ALGORITHM FOR LOW-EARTH ORBIT SATELLITE NETWORKS
Electrica, 2008 A new routing algorithm for Low-earth orbit (LEO) satellite networks is designed in this study. For this reason genetic algorithms are used. A new objective function is obtained to find the suitable path according to the criteria of the delay and an ...
Derya YILTAS
doaj +2 more sources