Results 81 to 90 of about 451,265 (323)
Teaching Computers to Think: Analysis of Artificial Intelligence and Connect Four [PDF]
, 2012 Connect Four is a classic two person, zero-sum game in which players utilize their wits and gravity to connect four of their own pieces in a horizontal, vertical, or diagonal row while blocking their opponent’s attempt to do the same. We have constructed
Baly, Kirk +4 more
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
, 2017 A novel approach for deriving the equation of state for a 2D lattice gas is proposed, based on arguments similar to those used in the derivation of the Langmuir-Szyszkowski equation of state for localized adsorption.
Darjani, Shaghayegh +2 more
core +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
The use of melatonin as a neuroprotector in the therapy of ischemic stroke
Медицинский совет, 2019 Statistics of the World Health Organization (WHO) show that the cerebrovascular disease is the second most frequent cause of death and the third – as the main disabling factor in the working age population.
M. G. Poluektov +2 more
doaj +1 more source
The Structure of Quantum Stochastic Processes with Finite Markov Order
, 2019 Non-Markovian quantum processes exhibit different memory effects when measured in different ways; an unambiguous characterization of memory length requires accounting for the sequence of instruments applied to probe the system dynamics.
Milz, Simon +3 more
core +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Blocking Adult Images Based on Statistical Skin Detection
ELCVIA Electronic Letters on Computer Vision and Image Analysis, 2004 This work is aimed at the detection of adult images that appear in Internet. Skin detection is of the paramount importance in the detection of adult images. We build a maximum entropy model for this task. This model, called the First Order Model in this paper, is subject to constraints on the color gradients of neighboring pixels.
Zheng, Huicheng +2 more
openaire +6 more sources
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source