Results 81 to 90 of about 440,099 (344)

Quantitative recurrence statistics and convergence to an extreme value distribution for non-uniformly hyperbolic dynamical systems [PDF]

, 2015
For non-uniformly hyperbolic dynamical systems we consider the time series of maxima along typical orbits. Using ideas based upon quantitative recurrence time statistics we prove convergence of the maxima (under suitable normalization) to an extreme ...
Holland, Mark, Rabassa, Pau, Sterk, Alef
core   +3 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Full counting statistics and shot noise of cotunneling in quantum dots and single-molecule transistors

, 2015
We develop a conceptually simple scheme based on a master-equation approach to evaluate the full-counting statistics (FCS) of elastic and inelastic off-resonant tunneling (cotunneling) in quantum dots (QDs) and molecules.
Belzig, Wolfgang, Kaasbjerg, Kristen
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The use of melatonin as a neuroprotector in the therapy of ischemic stroke

Медицинский совет, 2019
Statistics of the World Health Organization (WHO) show that the cerebrovascular disease is the second most frequent cause of death and the third – as the main disabling factor in the working age population.
M. G. Poluektov, A. M. Narbut, N. A. Shuvakhina   +2 more
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

“Distance‐Driven” Versus “Density‐Driven”: Understanding the Role of “Source‐Case” Distance and Gathering Places in the Localized Spatial Clustering of COVID‐19—A Case Study of the Xinfadi Market, Beijing (China)

GeoHealth, 2021
The frequent occurrence of local COVID‐19 today gives a strong necessity to better understand the effects of "source‐case" distance and gathering places, which are often considered to be the key factors of the localized spatial clustering of an epidemic.
Sui Zhang, Zhao Yang, Minghao Wang, Baolei Zhang   +3 more
doaj   +1 more source

Effect of baryon density on parton production, chemical equilibration and thermal photon emission from quark gluon plasma

, 1999
The effect of baryon density on parton production processes of $gg\rightleftharpoons ggg$ and $gg\rightleftharpoons q{\bar q}$ is studied using full phase space distribution function and also with inclusion of quantum statistics i.e.
A. Dumitru, A. K. Mohanty, C. T. Traxler, C. T. Traxler, D. Dutta, D. Dutta, D. K. Srivastava, D. K. Srivastava, D. K. Srivastava, D. Kharzeev, E. Braaten, E. Braaten, E. Braaten, E. Shuryak, H. Vija, J. Alam, J. D. Bjorken, J. Kapusta, K. Geiger, K. Geiger, K. Geiger, K. J. Eskola, K. Kumar, M. Strickland, P. Aurenche, P. Danielewicz, P. Levai, R. Baier, R. K. Choudhury, S. Chakrabarty, S. E. Vance, T. Altherr, T. Matsui, T. S. Biro   +33 more
core   +1 more source

High dimensional generalized empirical likelihood for moment restrictions with dependent data [PDF]

, 2014
This paper considers the maximum generalized empirical likelihood (GEL) estimation and inference on parameters identified by high dimensional moment restrictions with weakly dependent data when the dimensions of the moment restrictions and the parameters
Chang, Jinyuan, Chen, Song Xi, Chen, Xiaohong   +2 more
core   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source