Results 271 to 279 of about 330,080 (279)

Nanotechnology to Overcome Blood-Brain Barrier Permeability and Damage in Neurodegenerative Diseases. [PDF]

Pharmaceutics
Jiménez A, Estudillo E, Guzmán-Ruiz MA, Herrera-Mundo N, Victoria-Acosta G, Cortés-Malagón EM, López-Ornelas A.   +6 more
europepmc   +1 more source

Ligustrazine Alleviates Blood-Brain Barrier Damage by Downregulating Expression of miR-297c-5p. [PDF]

CNS Neurosci Ther
Guan S, Jiang R, Wang X, Chen T, Yi P, Li T, Ma T, Wang F.   +7 more
europepmc   +1 more source

MRI contrast accumulation in features of cerebral small vessel disease: blood-brain barrier dysfunction or elevated vascular density? [PDF]

Fluids Barriers CNS
Vikner T, Garpebring A, Björnfot C, Malm J, Eklund A, Wåhlin A.   +5 more
europepmc   +1 more source

Mannose Receptor C type 2 influences autoimmune neuroinflammation and blood-brain barrier integrity

Zierfuss B, Käch M, Sugère C, Morvan M, Desu H, Larouche S, Ahmed SB, Klement W, Thai K, Grasmuck C, Akbulak I, Tea F, Mechchate H, Margarido C, Bourbonniere L, Fournier A, Tastet O, Caron M, Selmi O, Krysak M, Kebir H, Dubé M, Haqqani A, Macaron G, Obaid S, Duquette P, Girard M, Behrendt N, Larochelle C, Arbour N, Zandee S, Prat A.   +31 more
europepmc   +1 more source

Blood-Brain Barrier Integrity and Transport of Major Hormones are Unchanged in Mice With Euglycemic Hyperinsulinemia.

Endocrinology
Niraula A, Hansen K, Bullock KM, Erickson MA, Banks WA.   +4 more
europepmc   +1 more source

Astrocyte CB₁receptors drive blood-brain barrier disruption in CNS inflammatory disease

Colomer T, Sánchez-Martín E, Bernal-Chico A, Moreno-García A, Serrat R, Baraibar A, Uribe-Irusta A, Iriarte-Sarria A, Skupio U, Matute C, Tepavcevic V, Fernández-Moncada I, Chapouly C, Marsicano G, Mato S.   +14 more
europepmc   +1 more source

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The potential off‐target neuroprotective effect of sister gliflozins suggests their repurposing despite not crossing the blood–brain barrier: From bioanalytical assay in rats into theory genesis

Journal of Separation Science, 2023
Gliflozins are successfully marketed antidiabetic agents with a reported neuroprotective effect, and this study tests their blood–brain barrier crossing ability. Henceforward, a computational hypothesis interpreting their effects was reasonable after failure to cross into the brain.
Moataz S. Hendy, Shereen Mowaka, Ehab F. Elkady, Asmaa El‐Zaher, Bassam M. Ayoub   +4 more
openaire   +2 more sources

Ras signaling and NO in oligodendrocytes modulate permeability of the blood–brain barrier

Nitric Oxide, 2014
Background: Ras is a small G-protein switch, activated when GTP-bound; in the GTP-bound state Ras signals to downstream effector proteins. GTPase inactivating proteins (GAPs) including neurofibromain (Nf1) accelerate hydrolysis of Ras-GTP to inactive Ras-GDP.
Titus-Mitchell, Haley, Rizvi, Tilat A, Mayes, Debra A., Miller, Shyra J., Ratner, Nancy   +4 more
openaire   +3 more sources

Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ€"Brain Barrier

2018
openaire   +1 more source