Results 71 to 80 of about 117,110 (303)

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques. [PDF]

, 2017
Zika virus (ZIKV) is a mosquito-transmitted virus that can cause severe defects in an infected fetus. ZIKV is also transmitted by sexual contact, although the relative importance of sexual transmission is unclear.
Busch, Michael, Carroll, Timothy, Dutra, Joseph, Fritts, Linda, Lanteri, Marion, Lo, Ming, Ma, Zhong-Min, Miller, Christopher J, O'Connor, Shelby, Rourke, Tracy, Silveira, Paola, Zarbock, Katie   +11 more
core   +1 more source

SARS-CoV-2 seroprevalence among people living with HIV in the German HIV-1 Seroconverter Cohort, 2020–2022

BMC Infectious Diseases
Objectives People living with HIV (PLWH) are a risk group for severe symptoms and higher mortality during COVID-19. We analyzed the dynamic rise of SARS-CoV-2 seroprevalence induced by coinfections and vaccinations in PLWH in the first three years of the
Oliver Hohn, Karolin Meixenberger, Alexander Volkwein, Kyra Körner, Suheda Icli, Uwe Koppe, Martin Hower, Viviane Bremer, Barbara Gunsenheimer-Bartmeyer, Norbert Bannert, the German HIV-1 Seroconverter Study Group   +10 more
doaj   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Infection caused by a parasite most closely related to Hepatozoon luiperdjie in cats from Hungary

Ticks and Tick-Borne Diseases
Feline hepatozoonosis, due to Hepatozoon felis, has been recently reported in wild cats from Central Europe. At the same time, only two isolated cases were reported in domestic cats, one in Austria, and another in Hungary. In the southern part of Central
Gergő Kürtös, Nóra Rácz, Viktória Kassay, Krisztián Olaszy, Zsuzsanna Vizi, Anna Szilasi, Nóra Takács, Gergő Keve, Barbara Tuska-Szalay, Sándor Hornok   +9 more
doaj   +1 more source

Evaluation of blood and bone marrow in selected canine vector-borne diseases

Parasites & Vectors, 2014
Background Bone marrow (BM) is a major hematopoietic organ that can harbour a variety of vector-borne pathogens; however, knowledge of BM pathological changes in dogs infected with vector-borne pathogens is limited. Thus, the aim of the present study was
Anna S De Tommasi, Domenico Otranto, Tommaso Furlanello, Silvia Tasca, Cinzia Cantacessi, Edward B Breitschwerdt, Dorothee Stanneck, Filipe Dantas-Torres, Gad Baneth, Gioia Capelli, Donato de Caprariis   +10 more
doaj   +1 more source

Multiplex-RT-PCR-ELISA panel for detecting mosquito-borne pathogens: Plasmodium sp. preserved and eluted from dried blood spots on sample cards

Malaria Journal, 2021
Background Children are the most vulnerable group affected by malaria and other tropical, vector-borne diseases in low-resource countries. Infants presenting with acute onset fever represent a major sector of outpatient care in the Lake Victoria region ...
Philip Koliopoulos, Neema Mathias Kayange, Tim Daniel, Florian Huth, Britta Gröndahl, Grey Carolina Medina-Montaño, Leah Pretsch, Julia Klüber, Christian Schmidt, Antke Züchner, Sebastian Ulbert, Steven E. Mshana, Marylyn Addo, Stephan Gehring   +13 more
doaj   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Comparison and complete mitogenomes of two morphologically similar but ecologically different tick species, Ixodes arboricola and Ixodes lividus (subgenus Pholeoixodes)

Ticks and Tick-Borne Diseases
Ixodes arboricola and Ixodes lividus are ornithophilic tick species. The former is typically associated with tree-hole dwelling birds, while the latter is a host-specific parasite of sand martins (Riparia riparia).
Sándor Hornok, Paulina Lesiczka, Tim Warbroek, Tijs J.M. van den Bosch, Andor Pitó, Gergő Keve, Nóra Takács, Jenő Kontschán, Attila D. Sándor   +8 more
doaj   +1 more source

Thermo‐Fluorescent Bactericidal Quantum Dots Based Smart Multifunctional Textiles via Molecular Surface Engineering and 3D‐Printed Interlocked Architectures

Advanced Healthcare Materials, EarlyView.
A versatile approach is presented for fabricating smart multifunctional textiles by integrating thermo‐fluorescent carbon dot/polymer nanocomposite coatings with 3D‐printed interlocked architectures. The fabrics exhibit temperature‐responsive fluorescence, durable hydrophobicity, strong antibacterial and antioxidant activity, and enhanced UV protection.
Poushali Das, Sayan Ganguly, Parham Khoshbakht Marvi, Misha Muthalali, Fatemeh Parniani, Shiza Hassan, Xiaowu (Shirley) Tang, Seshasai Srinivasan, Amin Reza Rajabzadeh   +8 more
wiley   +1 more source