Results 91 to 100 of about 779,380 (305)

Anti‐A Production by a Group 0 Spleen Transplanted to a Group A Recipient [PDF]

open access: yes, 1985
. A group A1 diabetic received a pancreas‐spleen transplant from a group 0 donor. Severe immune hemolysis due to anti‐A ensued, requiring graft splenectomy. The transplanted spleen can be a potent source of blood group antibody. © 1985 S.
Beck   +9 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

Distribution of feline AB blood types: a review of frequencies and its implications in the Iberian Peninsula

open access: yesJournal of Feline Medicine and Surgery Open Reports, 2017
Objectives The objective of this study was to document the prevalence of feline blood types in the Iberian Peninsula and to determine the potential risk of incompatibility-related transfusion reactions in unmatched transfusions and the potential risk of ...
Sandrina M Vieira   +8 more
doaj   +1 more source

216 Jewish Hospital of St. Louis [PDF]

open access: yes, 1975
https://digitalcommons.wustl.edu/bjc_216/1131/thumbnail ...

core   +1 more source

Validation of a Polymerase Chain Reaction technique for Kidd blood group genotyping [PDF]

open access: yes, 2015
The Kidd blood group antigens, Jkª and Jkᵇ , are two of the main surface markers which are found on the membrane of red blood cells. The determination of whether a donor or a recipient has the Jkª and/or the Jkᵇ antigens is crucially important to ...
Borg, Joseph J.   +2 more
core   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Genetic Testing for Inherited Thrombophilia: 20 Years of Experience in a University and Tertiary Care Centre

open access: yesProceedings, 2018
Inherited thrombophilias are a group of clinical conditions in which there is a genetic variant defect associated with a predisposition to thrombosis. Genetic testing for inherited thrombophilias has been used in the diagnosis of specific thrombophila at
Cláudia Vaz   +9 more
doaj   +1 more source

Modelling very large complex systems using distributed simulation: A pilot study in a healthcare setting [PDF]

open access: yes, 2006
Modern manufacturing supply chains are hugely complex and like all stochastic systems, can benefit from simulation. Unfortunately supply chain systems often result in massively large and complicated models, which even today’s powerful computers cannot ...
Brailsford, S   +3 more
core   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

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