Results 101 to 110 of about 779,380 (305)
Advanced Science, EarlyView.Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen +14 more
wiley +1 more source
Barnes Hospital Bulletin [PDF]
, 1978 https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1154/thumbnail ...
core +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
, 1981 This item contains two issues of the Take One newsletter: September 3, and 17, 1981Take One was published every two weeks and focused on short news items and announcements "for the people of University Hospital.
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Advanced Science, EarlyView.ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang +8 more
wiley +1 more source
216 Jewish Hospital of St. Louis [PDF]
, 1959 https://digitalcommons.wustl.edu/bjc_216/1044/thumbnail ...
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Advanced Science, EarlyView.This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun +19 more
wiley +1 more source
Retinal vessel segmentation using Gabor Filter and Textons [PDF]
, 2014 This paper presents a retinal vessel segmentation method that is inspired by the human visual system and uses a Gabor filter bank. Machine learning is used to optimize the filter parameters for retinal vessel extraction.
Fisher, Mark, Wang, Wenjia, Zhang, Lei
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Advanced Science, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang +9 more
wiley +1 more source