Results 81 to 90 of about 742,048 (314)
216 Jewish Hospital of St. Louis [PDF]
https://digitalcommons.wustl.edu/bjc_216/1044/thumbnail ...
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Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao+9 more
wiley +1 more source
Know your HIV epidemic (KYE) report: review of the HIV epidemic in South Africa.
In order to update and consolidate South Africa’s evidence base for HIV-prevention interventions, it was decided by the Government of South Africa to commission a synthesis of the available data on the epidemiology of prevalent and incident HIV ...
Chikwava, Fadzai+6 more
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This item contains two issues of the Take One newsletter: September 3, and 17, 1981Take One was published every two weeks and focused on short news items and announcements "for the people of University Hospital.
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Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy
Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao+8 more
wiley +1 more source
Use of recombinant antigens for the diagnosis of Chagas disease and blood bank screening [PDF]
Elza Almeida+4 more
openalex +1 more source
Triple‐negative breast cancer (TNBC) remains a major challenge in breast cancer management as it lacks effective therapeutic targets. This study uncovers that MYC/TET3‐regulated mitochondrial inner‐membrane protein TMEM65 promotes TNBC progression and cisplatin resistance by activating the OXPHOS‐SERPINB3 pathway and reveals TMEM65 as a potential ...
Yin‐Ling Zhang+10 more
wiley +1 more source
Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion. [PDF]
Jackson M+5 more
europepmc +1 more source