Results 161 to 170 of about 365,373 (345)

Banking on Blood [PDF]

EBioMedicine, 2016
openaire   +3 more sources

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

A critical review of the applicability of serological screening for Leishmaniasis in blood banks in Brazil. [PDF]

J Parasit Dis, 2021
Rodrigues WF, Mendes NS, de Carvalho Ribeiro P, Mendes Filho D, Parreira RC, Chaves KCB, de Abreu MCM, Miguel CB.   +7 more
europepmc   +1 more source

Residual risk of HIV transmission through blood transfusion in five blood banks in Cameroon

, 2020
Elvige Geukeng Dongmo, Dickson Shey Nsagha, Dénis Zofou, Anna Longdoh Njunda, Aubin Nanfack, Joseph Fokam, Claude Tayou Tagny, Alexis Ndjolo   +7 more
openalex   +1 more source

Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected withnef-Defective HIV Type 1 [PDF]

, 1999
Wayne B. Dyer, Graham S. Ogg, Marie‐Ange Demoitié, Xia Jin, Andrew F. Geczy, Sarah Rowland‐Jones, Andrew J. McMichael, Douglas F. Nixon, John S. Sullivan   +8 more
openalex   +1 more source

Guards at Red Cross Blood Bank, Los Angeles, Calif., 1942

, 2021
Unknown
openalex   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

External quality control program in infectious diseases screening at laboratories and blood banks in Latin America: an analysis of the past 5 years. [PDF]

Rev Panam Salud Publica, 2023
Mendrone-Junior A, Salles N, Otani M, Countinho A, Alves LBO, Rocha V, Beltrán-Durán M.   +6 more
europepmc   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

Challenges associated with blood banks and blood donations during the COVID-19 pandemic. [PDF]

Am J Emerg Med, 2021
Sen-Crowe B, McKenney K, McKenney M, Elkbuli A.   +3 more
europepmc   +1 more source