Results 171 to 180 of about 43,686 (256)
BMEMat, EarlyView.The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng +7 more
wiley +1 more source
A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer
BMEMat, EarlyView.The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue +8 more
wiley +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
Biological Reviews, EarlyView.ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
From Promise to Practice: A Systematic Review of Sustainability‐Linked Loans
Business Strategy and the Environment, EarlyView.ABSTRACT By linking loan terms to predefined environmental, social and governance (ESG) goals, sustainability‐linked loans (SLLs) can incentivise banks and corporations towards sustainability. Despite rapid growth, research remains scant and questions remain about SLLs' financial, organisational and sustainability impacts and how they differ from other
Elias Porse, Aurélien Acquier
wiley +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, EarlyView.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson +7 more
wiley +1 more source
Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum
Clinical Anatomy, EarlyView.ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery +4 more
wiley +1 more source
Bacterial contaminants of stored blood and blood components ready for transfusion at blood banks in Mekelle, Northern Ethiopia. [PDF]
BMC Res Notes, 2019 Agzie M +4 more
europepmc +1 more source