Results 61 to 70 of about 365,373 (345)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

Adipokines and Associations With Incident Osteoporotic Fracture in Patients With Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, and fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker   +9 more
wiley   +1 more source

Co-digestion of the mechanically recovered organic fraction of municipal solid waste with slaughterhouse wastes

open access: yes, 2012
The current work aimed to resolve some long-standing questions about the potential benefits and limitations of co-digestion of slaughterhouse wastes.
Banks, C.J., Zhang, Y.
core   +1 more source

Survey of the Reduviidae (Heteroptera) of Southern Illinois, Excluding the Phymatinae, With Notes on Biology [PDF]

open access: yes, 2018
A survey of the nonphymatine reduviids of southern Illinois was con­ducted from April 1996 to November 1998. In addition to county distributions, information was collected on times of occurrence of adults and nymphs and associated habitats.
Hagerty, A. M, McPherson, J. E
core   +3 more sources

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis‐Associated Interstitial Lung Disease Risk

open access: yesArthritis Care &Research, Accepted Article.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase (MMP)‐7, and serum anti‐malondialdehyde‐acetaldehyde (anti‐MAA) antibody for RA‐associated interstitial lung disease risk stratification. Methods Using a multicenter cohort of US veterans with RA, we performed a cross‐
Kelsey Coziahr   +16 more
wiley   +1 more source

Tamización de malaria en donantes de sangre de Cali, Colombia.

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2005
Introducción. En Colombia existe déficit de unidades de sangre. En ciudades como Cali este déficit se agrava por el rechazo de donantes debido al riesgo de transmitir malaria; aunque en la ciudad no hay transmisión de malaria, está próxima a la Costa ...
Carmen M. Castillo, Carolina Ramírez
doaj   +1 more source

Umbilical Cord Blood Banking [PDF]

open access: yes, 2007
[À l'origine dans / Was originally part of : CRDP - Droit, biotechnologie et rapport au milieu]The umbilical cord, previously considered as waste and discarded at birth, is a source of haematopoietic stem cells. Current therapeutic uses of umbilical cord
Bordet, Sylvie   +2 more
core   +2 more sources

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]

open access: yes, 2017
The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria   +5 more
core   +1 more source

Modelling the blood bank inventory: simple formulae for stock management in clinical settings [PDF]

open access: gold, 2022
S. Vaz   +7 more
openalex   +1 more source

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