Results 161 to 170 of about 4,638,350 (355)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

IN VITRO AUGMENTATION OF MACROPHAGE-ACTIVATING-FACTOR RELEASE FROM PERIPHERAL BLOOD CELLS OF CANCER PATIENTS BY A DNA FRACTION FROM MYCOBACTERIUM BOVIS BCG

, 1990
Harukazu Mashiba, Keiko Matsunaga, Hirotsugu Tomoda, Motonosuke Furusawa   +3 more
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

P1550: NEW GENERATION EKTACYTOMETRY STUDY OF RED BLOOD CELLS RHEOLOGICAL PARAMETERS IN HEMOGLOBINOPATHIES

HemaSphere, 2022
E. Krishnevskaya, M. Molero Magariño, Á. Ancochea Serra, J.-L. Vives Corrons, I. Hernandez, V. Leguizamón   +5 more
doaj   +1 more source

Dynamic changes in clot formation determined using thromboelastometry after reinfusion of unwashed anticoagulated cell-salvaged whole blood in total hip arthroplasty.

, 2015
Bernd Froessler, Ingo Weber, Nicolette A. Hodyl, Khaschayar Saadat-Gilani   +3 more
openalex   +1 more source

Ray Optics Model for Optical Trapping of Biconcave Red Blood Cells [PDF]

, 2022
R. Tognato, Philip H. Jones
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Leukemia‐Derived Dendritic Cells can be Generated from Blood or Bone Marrow Cells from Patients with Acute Myeloid Leukaemia: A Methodological Approach under Serum‐Free Culture Conditions [PDF]

, 2005
Stefanie Kufner, Horst Zitzelsberger, Tanja Kroell, R. Pelka‐Fleischer, Alireza Salem, F. De Valle, C. Schweiger, V. Nuessler, Christoph Schmid, Hans-Jochen Kölb, Helga Schmetzer   +10 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Immobilized Enzymes for ABO-Independent Blood Cell Transfusions. [PDF]

Chembiochem
Möller C, Pohlschröder F, Wesche J, Schmiade P, Baselau M, Wende K, Stloukalová B, Böttcher D, Greinacher A, Bornscheuer UT, Terholsen H, Aurich K.   +11 more
europepmc   +1 more source