Results 171 to 180 of about 4,638,350 (355)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Amphiregulin as a biomarker for monitoring lifethreatening acute graft-versus-host disease: secondary analysis of two prospective clinical trials

Haematologica, 2023
Shernan G. Holtan, Najla El Jurdi, Armin Rashidi, Brian C. Betts, Connor Demorest, John P Galvin, Margaret L. MacMillan, Daniel J. Weisdorf, Angela Panoskaltsis-Mortari, Michael A. Pratta   +9 more
doaj   +1 more source

Deep generative classification of blood cell morphology. [PDF]

Nat Mach Intell
Deltadahl S, Gilbey J, Van Laer C, Boeckx N, Leers MPG, Freeman T, Aiken L, Farren T, Smith M, Zeina M, MacDonald S, Gleghorn D, BloodCounts! consortium, Rudd JH, Piazzese C, Taylor J, Gleadall N, Schönlieb CB, Sivapalaratnam S, Roberts M, Nachev P.   +20 more
europepmc   +1 more source

Effectiveness of Natural Killer (NK) Cells in Peripheral Blood Stem-Cell towards Expression of EZH2, Ki-67, and Apoptosis in Retinoblastoma (RB) Cells Culture

, 2015
Hendrian Dwikoloso Soebagjo, Susy Fatmariyanti, Delfitri Lutfi   +2 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Cognitive impairment is associated with altered blood cell profiles in aggressive lymphoma. [PDF]

Support Care Cancer
McCaffrey D, Gates P, Dhillon HM, Wilson C, Vardy JL, Weickert CS, Walker AK.   +6 more
europepmc   +1 more source

The effects of retinol onin vitroimmunoglobulin synthesis by cord blood and adult peripheral blood mononuclear cells [PDF]

, 1993
W WANG, Joseph L. Napoli, Mark Ballow
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

P1617: CLINICAL SIGNIFICANCE OF CYTOMEGALOVIRUS DRUG RESISTANCE GENE MUTATIONS IN CYTOMEGALOVIRUS INFECTION AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

HemaSphere, 2022
D. yang, J. wen, Y. zhang, G. li, Y. zheng, S. chen, A. pang, Y. he, J. wei, Q. ma, W. zhai, R. zhang, X. chen, S. feng, M. han, E. jiang   +15 more
doaj   +1 more source

Just-in-time display of minor red blood cell antibodies. [PDF]

Transfusion
Pettit M, Winstead R, Atchison K, Mueller A, Andrews J.   +4 more
europepmc   +1 more source