Results 11 to 20 of about 2,511,432 (323)

Real-time stain-free classification of cancer cells and blood cells using interferometric phase microscopy and machine learning [PDF]

open access: yesCytometry A 99: 511-523, 2021, 2021
We present a method for a real time visualization and automatic processing for detection and classification of untouched cancer cells in blood during stain free imaging flow cytometry using digital holographic microscopy and machine learning in throughput of 15 cells per second.
arxiv   +1 more source

Blood Cells and Blood Cell Development in the Animal Kingdom [PDF]

open access: yesAnnual Review of Cell and Developmental Biology, 2006
Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrate phyla. This has led to a renewed interest regarding homologies between blood cell types and their developmental origin among different animals.
openaire   +4 more sources

Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures

open access: yesStem Cell Research & Therapy, 2018
Background Senescent cells are undesirable in cell therapy products due to reduced therapeutic activity and risk of aberrant cellular effects, and methods for assessing senescence are needed. Early-passage mesenchymal stromal cells (MSCs) are known to be
S. Oja   +4 more
doaj   +1 more source

Autophagy in cells of the blood

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
Autophagy is a conserved proteolytic mechanism that degrades cytoplasmic material including cell organelles. The importance of autophagy for cell homeostasis and survival has long been appreciated. Recent data suggest that autophagy is also involved in non-metabolic functions that particularly concern blood cells.
Shida Yousefi, Hans-Uwe Simon
openaire   +3 more sources

The Red Blood Cells on the Move! [PDF]

open access: yesFrontiers in Physiology, 2018
Following the steps of the founders of modern red blood cell (RBC) research (e.g., Ørskov, 1935; Wilbrandt, 1937; Cohn and Cohn, 1939; Ponder, 1948; Pauling et al., 1949), we answer to the growing need of a platform to share and discuss the new findings, argue and move forward in our understanding of these amazing cells.
Bogdanova, Anna, Kaestner, Lars
openaire   +5 more sources

An Imaging Flow Cytometry Method to Measure Citrullination of H4 Histone as a Read-out for Neutrophil Extracellular Traps Formation

open access: yesBio-Protocol, 2021
The formation of neutrophil extracellular traps (NETs) is thought to play a critical role in infections and propagating sterile inflammation. Histone citrullination is an essential and early step in NETs formation, detectable prior to the formation of ...
Emilia Barbu   +3 more
doaj   +1 more source

Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10

open access: yesBMC Immunology, 2017
Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used.
Unni Gopinathan   +6 more
doaj   +1 more source

Bloodstream infections due to Carbapenem-Resistant Enterobacteriaceae in hematological patients: assessment of risk factors for mortality and treatment options

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2023
Purpose Bloodstream infection (BSI) caused by Carbapenem-Resistant Enterobacteriaceae (CRE) are associated with poor outcomes in hematological patients.
Lining Zhang   +12 more
doaj   +1 more source

Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 spike protein

open access: yesNature Communications, 2023
SARS-CoV-2 infection can cause coagulopathic events. Kuhn et al. show by cryo-ET how the Spike protein impacts platelet morphology by binding to the platelet surface, leading to micro-activation; and investigate integrin as possible point of contact.
Christopher Cyrus Kuhn   +10 more
doaj   +1 more source

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