Results 61 to 70 of about 1,196,434 (355)

Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting [PDF]

, 2007
Background: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior ...
Buchan, Keith G., Croal, Bernard L., Cuthbertson, Brian, El-Shafei, Hussein, Gibson, George, Gibson, Patrick H., Hillis, Graham S., Ifezulike, Ada I., Jeffrey, Robert R., Small, Gary R.   +9 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

FEASIBILITY OF COLLECTING UMBILICAL CORD BLOOD IN JORDAN AND THE EFFECT OF MATERNAL AND NEONATAL FACTORS ON HEMATOPOIETIC STEM CELL CONTENT

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Background: Cord blood transplant is an accepted treatment for many malignant and non-malignant diseases. We sought to determine the feasibility of collecting cord blood in Jordan and the effect of maternal and fetal factors on the quality of the cord ...
Ayad Ahmed Hussein, Randa M. Bawadi, Lubna H. Tahtamouni, Haydar Frangoul, Ali Z. ElKarmi   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

What is the origin of the normal ranges of blood cell counts? An evolutionary perspective

eJHaem
Background The normal values of the complete blood count are part of the foundational medical knowledge that is seldom questioned due to their well‐established nature.
Manon Zala, Vincent Alcazer, Laetitia Largeaud, Pierre Sujobert   +3 more
doaj   +1 more source

Predictive Values of White Blood Cell Count in Peripheral Blood at Admission on In-Hospital Complications and 90-Day Outcomes of Patients with Aneurysmal Subarachnoid Hemorrhage: Insights from the LongTEAM Registry

Journal of Inflammation Research, 2022
Runting Li,1 Yuanli Zhao,1– 4 Xiaolin Chen,1,3,4 Qiang Hao1 1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2China National Clinical Research Center for Neurological Diseases ...
Li R, Zhao Y, Chen X, Hao Q
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Haematological values in a healthy adult population in Yaoundé, Cameroon

African Journal of Laboratory Medicine, 2019
Background: Haematological values derived from local populations are useful in laboratories to improve diagnoses for local patients. In Cameroon, these data are not yet available.
Martin E. Oloume, Abas Mouliom, Bernard F. Melingui, Suzanne Belinga, Julie S. Nana, Mathurin Tejiokem, Francoise N. Sack, Jeanne Manga, Annie R. Epote   +8 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Causal associations of white blood cell count and sudden sensorineural hearing loss: a bidirectional and multivariable Mendelian randomization study

Frontiers in Neurology
BackgroundNumerous compelling observational studies have demonstrated a plausible correlation between the white blood cell count and the susceptibility to sudden sensorineural hearing loss (SSNHL).
Ling Zhang, Jialei Chen, Jialei Chen, Jialei Chen, Shixun Zhong, Jing Luo, Jing Luo, Ping Tang   +7 more
doaj   +1 more source