Results 81 to 90 of about 747,398 (307)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Red blood cell count as an indicator of microvascular complications in Chinese patients with type 2 diabetes mellitus

open access: yesVascular Health and Risk Management, 2013
Zhan-Sheng Wang,1,2 Zhan-Chun Song,1 Jing-Hui Bai,1 Fei Li,3 Tao Wu,1 Ji Qi,2 Jian Hu11Department of Cardiology, First Affiliated Hospital of China Medical University, 2Second Department of Cardiology, Fourth People's Hospital of Shenyang, Shenyang ...
Wang ZS   +6 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Complete Blood Count (CBC) and Multivariate Analysis as Tools for Predicting Coronavirus (COVID-19) Infectious [PDF]

open access: yes
The COVID-19 pandemic has affected millions worldwide in recent years. However, the epidemic's impact on the residents of the southern Libyan region has not been assessed.
Fatimah Nouri Mohammed Abdulwahid   +3 more
core   +1 more source

Evaluation of Plateletcrit and Neutrophil/Lymphocyte, Monocyte/Lymphocyte and Platelet/Lymphocyte Ratios in Endometrial Polyp

open access: yesİstanbul Medical Journal, 2020
Introduction:To evaluate the association between endometrial polyp (EP) and inflammatory markers such as neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte/lymphocyte ratio (MLR) and plateletcrit (PCT).Methods:In this ...
Anıl Turhan Çakır, İsa Şükrü Öz
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Identification of asthma phenotypes using blood cell count

open access: yesEBioMedicine, 2022
Andriana I Papaioannou   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A novel method to count the red blood cells in thin blood films

open access: yes, 2011
This paper describes a novel idea to identify the total number of red blood cells (RBCs) as well as their location in a Giemsa stained thin blood film image.
Morling, R.C.S.   +3 more
core   +1 more source

Hematological changes of Anemia`s in Horses of Equestrian club in Baghdad

open access: yesThe Iraqi Journal of Veterinary Medicine, 2012
This study was conducted to know thehematological changes of anemia in horsesat equestrian club in Baghdad. Blood samples were collected from 151 horses of both sexes(74 male and 77 female) and different agesrandomly.
Faisal G. Habasha
doaj   +1 more source

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