Results 101 to 110 of about 4,387,004 (356)

MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1

Stem Cell Reports, 2018
Summary: Human pluripotent stem cells (hPSCs) provide an unlimited source for generating various kinds of functional blood cells. However, efficient strategies for generating large-scale functional blood cells from hPSCs are still lacking, and the ...
Hongtao Wang, Cuicui Liu, Xin Liu, Mengge Wang, Dan Wu, Jie Gao, Pei Su, Tatsutoshi Nakahata, Wen Zhou, Yuanfu Xu, Lihong Shi, Feng Ma, Jiaxi Zhou   +12 more
doaj   +1 more source

Downregulation of mapk/mak/mrk overlapping kinase 1 in peripheral blood mononuclear cells of pediatric patients with type 1 diabetes mellitus [PDF]

, 2021
Miron Sopić, Ana Ninić, Barbara Ostanek, Dragana Bojanin, Tatjana Milenković, Jelena Munjas, Marija Mihajlović, Jelena Vekić, Janja Marc, Vesna Spasojević‐Kalimanovska   +9 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Nutritional status indices on the prognosis of patients with relapsed and refractory multiple myeloma treated with CAR-T cell immunotherapy

Frontiers in Nutrition
Background aimsChimeric antigen receptor (CAR) T-cell therapy shows remarkable efficacy against relapsed/refractory multiple myeloma (R/R MM). Nutritional status, assessed by objective indices like the Controlling Nutritional Status (CONUT) and ...
Peng Xu, Peng Xu, Peng Xu, Yang Liu, Yang Liu, Yang Liu, Yawen Wang, Yawen Wang, Yawen Wang, Qiwen Feng, Qiwen Feng, Qiwen Feng, Huanxin Zhang, Huanxin Zhang, Huanxin Zhang, Hai Cheng, Hai Cheng, Hai Cheng, Kunming Qi, Kunming Qi, Kunming Qi, Kailin Xu, Kailin Xu, Kailin Xu, Zhenyu Li, Zhenyu Li, Zhenyu Li   +26 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy

Frontiers in Immunology
BackgroundIn recent years, chimeric antigen receptor (CAR)-T cell therapy has achieved tremendous efficacy in relapsed/refractory multiple myeloma (R/R MM).
Lingling Yin, Lingling Yin, Lingling Yin, Bin Lv, Bin Lv, Jiao Ge, Yuekun Qi, Yuekun Qi, Yuekun Qi, Jieyun Xia, Jieyun Xia, Jieyun Xia, Sha Ma, Sha Ma, Sha Ma, Ying Wang, Ying Wang, Ying Wang, Yang Liu, Yang Liu, Yang Liu, Dian Zhou, Dian Zhou, Dian Zhou, Jiang Cao, Jiang Cao, Jiang Cao, Zhiling Yan, Zhiling Yan, Zhiling Yan, Kunming Qi, Kunming Qi, Kunming Qi, Wei Sang, Wei Sang, Wei Sang, Depeng Li, Depeng Li, Depeng Li, Hai Cheng, Hai Cheng, Hai Cheng, Wei Chen, Wei Chen, Wei Chen, Kailin Xu, Kailin Xu, Kailin Xu, Weiying Gu, Zhenyu Li, Zhenyu Li, Zhenyu Li, Feng Zhu, Feng Zhu, Feng Zhu   +54 more
doaj   +1 more source

Correction to “Classification of β-Thalassemia Carriers From Red Blood Cell Indices Using Ensemble Classifier” [PDF]

, 2021
Saima Sadiq, Muhammad Usman Khalid, Mui-zzud-din, Saleem Ullah, Waqar Aslam, Arif Mehmood, Gyu Sang Choi, Byung-Won On   +7 more
openalex   +1 more source

Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression

, 2016
Angiogenesis involves the formation of new blood vessels by sprouting or splitting of existing blood vessels. During sprouting, a highly motile type of endothelial cell, called the tip cell, migrates from the blood vessels followed by stalk cells, an ...
Dallinga, Marchien G., Klaassen, Ingeborg, Merks, Roeland M. H., Palm, Margriet M., Schlingemann, Reinier O., van Dijk, Erik   +5 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

U-shaped association of the stress hyperglycemia ratio with all-cause mortality and premature death in patients with cardiovascular disease: a cohort study

Diabetology & Metabolic Syndrome
Background The stress hyperglycemia ratio (SHR) is recognized as a significant indicator of relative hyperglycemia that has demonstrated to correlate with poor outcomes, including elevated mortality rates in individuals facing severe acute conditions ...
Na Wang, Ya Shao, Yan Zhan, Meiling Shao, Bin Liu, Longti Li, Huiqin Zhong   +6 more
doaj   +1 more source