Results 51 to 60 of about 2,454,570 (173)

Trimethylamine N-oxide promotes the proliferation and migration of hepatocellular carcinoma cell through the MAPK pathway

open access: yesDiscover Oncology
Trimethylamine-n-oxide (TMAO) is a metabolite of intestinal flora following the consumption of phosphatidylcholine-rich foods. Clinical cohort studies have shown that plasma TMAO may be a risk factor for cancer development, including hepatocellular ...
Chunfang Zhou   +6 more
doaj   +1 more source

The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy

open access: yesFrontiers in Immunology
BackgroundIn recent years, chimeric antigen receptor (CAR)-T cell therapy has achieved tremendous efficacy in relapsed/refractory multiple myeloma (R/R MM).
Lingling Yin   +54 more
doaj   +1 more source

A model for red blood cells in simulations of large-scale blood flows [PDF]

open access: yesarXiv, 2011
Red blood cells (RBCs) are an essential component of blood. A method to include the particulate nature of blood is introduced here with the goal of studying circulation in large-scale realistic vessels. The method uses a combination of the Lattice Boltzmann method (LBM) to account for the plasma motion, and a modified Molecular Dynamics scheme for the ...
arxiv  

Mathematical modeling of blood flow through arterial bifurcation [PDF]

open access: yesarXiv, 2020
The blood vascular system consists of blood vessels such as arteries, arterioles, capillaries and veins that convey blood throughout the body. The pressure difference which exists between the ends of the vessels provides the living force required to the flow of blood.
arxiv  

TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy

open access: yesEpigenetics
Methylation modifications play pertinent roles in regulating gene expression and various biological processes. The silencing of the demethylase enzyme TET1 can affect the expressions of key oncogenes or tumour suppressor genes, thus contributing to ...
Ji Ren   +6 more
doaj   +1 more source

Cross-sectional focusing of red blood cells in a constricted microfluidic channel [PDF]

open access: yesarXiv, 2019
Constrictions in blood vessels and microfluidic devices can dramatically change the spatial distribution of passing cells or particles and are commonly used in biomedical cell sorting applications. However, the three-dimensional nature of cell focusing in the channel cross-section remains poorly investigated.
arxiv  

Saikogenin A improves ethanol-induced liver injury by targeting SIRT1 to modulate lipid metabolism

open access: yesCommunications Biology
Chronic alcohol consumption can lead to alcohol live disease (ALD). Steatosis is a critical hallmark of ALD, making it an important stage for therapeutic intervention.
Mingzhu Jiang   +9 more
doaj   +1 more source

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