Results 71 to 80 of about 2,454,570 (173)

Categorising hybrid material microfluidic devices

Frontiers in Lab on a Chip Technologies
Microfluidic devices are useful tools for a wide range of biomedical, industrial, and environmental applications. Hybrid microfluidic devices utilising more than two materials are increasingly being used for their capacity to produce unique structures ...
Tom Carvell, Paul Burgoyne, Alasdair R. Fraser, Helen Bridle   +3 more
doaj   +1 more source

Transforming Blood Cell Detection and Classification with Advanced Deep Learning Models: A Comparative Study [PDF]

arXiv
Efficient detection and classification of blood cells are vital for accurate diagnosis and effective treatment of blood disorders. This study utilizes a YOLOv10 model trained on Roboflow data with images resized to 640x640 pixels across varying epochs. The results show that increased training epochs significantly enhance accuracy, precision, and recall,
arxiv  

Partial Inhibition of Epithelial-to-Mesenchymal Transition (EMT) Phenotypes by Placenta-Derived DBMSCs in Human Breast Cancer Cell Lines, In Vitro

Cells
Stem cell-based therapies hold significant potential for cancer treatment due to their unique properties, including migration toward tumor niche, secretion of bioactive molecules, and immunosuppression.
Yasser Basmaeil, Abdullah Al Subayyil, Haya Bin Kulayb, Altaf A. Kondkar, Maha Alrodayyan, Tanvir Khatlani   +5 more
doaj   +1 more source

A Study of the Morphology of the Living Cells of Blood and Bone Marrow in Vital Films with the Phase Contrast Microscope [PDF]

, 1955
G. Adolph Ackerman, NICHOLAS C. BELLIOS
openalex   +1 more source

Generation, establishment and characterization of a pluripotent stem cell line (CVTTHi001-A) from primary fibroblasts isolated from a patient with activated PI3 kinase delta syndrome (APDS2)

Stem Cell Research, 2020
APDS2 is caused by mutations in PIK3R1 gene resulting in constitutive PI3Kδ activation. PI3Kδ is predominantly expressed in leukocytes and plays critical roles in regulating immune responses.
M. Inglés-Ferrándiz, M. Martin-Inaraja, L. Herrera, M. Villaverde, S. Santos, M.A. Vesga, E. Garreta, I. Martín-Ruiz, A.M. Aransay, J. Anguita, B. Barreña, L.M. Allende, L.I. Gonzalez-Granado, C. Eguizabal   +13 more
doaj  

LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation

Cell Reports, 2020
Summary: Attempts to generate functional blood cells from human pluripotent stem cells (hPSCs) remain largely unsuccessful, mainly due to the lack of understanding of the regulatory network of human hematopoiesis.
Yu Wang, Hongtao Wang, Jiaojiao Guo, Jie Gao, Mengge Wang, Meijuan Xia, Yuqi Wen, Pei Su, Ming Yang, Mingyao Liu, Lihong Shi, Tao Cheng, Wen Zhou, Jiaxi Zhou   +13 more
doaj  

In Vitro Biocompatibility Assessment of Bioengineered PLA-Hydrogel Core–Shell Scaffolds with Mesenchymal Stromal Cells for Bone Regeneration

Journal of Functional Biomaterials
Human mesenchymal stromal cells (hMSCs), whether used alone or together with three-dimensional scaffolds, are the best-studied postnatal stem cells in regenerative medicine.
Federica Re, Luciana Sartore, Chiara Pasini, Matteo Ferroni, Elisa Borsani, Stefano Pandini, Andrea Bianchetti, Camillo Almici, Lorena Giugno, Roberto Bresciani, Silvia Mutti, Federica Trenta, Simona Bernardi, Mirko Farina, Domenico Russo   +14 more
doaj   +1 more source

Action of Hypotonic, Isotonic and Hypertonic Solutions upon the Blood, Muscle and Nerve Tissue Cells of Living Animals [PDF]

, 1922
Ira G. Nichols
openalex   +1 more source

MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1

Stem Cell Reports, 2018
Summary: Human pluripotent stem cells (hPSCs) provide an unlimited source for generating various kinds of functional blood cells. However, efficient strategies for generating large-scale functional blood cells from hPSCs are still lacking, and the ...
Hongtao Wang, Cuicui Liu, Xin Liu, Mengge Wang, Dan Wu, Jie Gao, Pei Su, Tatsutoshi Nakahata, Wen Zhou, Yuanfu Xu, Lihong Shi, Feng Ma, Jiaxi Zhou   +12 more
doaj  

Discovery of oxazine-linked pyrimidine as an inhibitor of breast cancer growth and metastasis by abrogating NF-κB activation

Frontiers in Oncology
IntroductionNuclear factor kappa (NF-κB) plays a key role in cancer cell proliferation; thus, small molecule inhibitors of NF-κB activity can effectively inhibit breast cancer (BC) progression.
Jie Yuan, Bhanuprakash C. Narasimhachar, Bhanuprakash C. Narasimhachar, Akshay Ravish, Li Yang, Hua Zhang, Qun Wang, Zhi Li, Jun Huang, Bei Wang, Geng Wang, Keshav Kumar Harish, Arunachalam Chinnathambi, Chandramohan Govindasamy, Mahendra Madegowda, Basappa Basappa   +15 more
doaj   +1 more source