Results 71 to 80 of about 4,387,004 (356)

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Optimal large‐scale CD34+ enrichment from a leukapheresis collection using the clinimacs prodigy platform

Clinical Case Reports, 2020
Optimization of Hematology Patient's treatment: It is possible to obtain a 100% CD34+ recovery after CD34+ selection using the CliniMACS Prodigy.
Oscar M. Pello, Diego Lanzarot, Mercedes Colorado, Cristina Amunarriz, Andrés Insunza, Lorena Álvarez‐Rodríguez, María Díez de Velasco, Natividad Sainz‐Sainz, José Luis Arroyo   +8 more
doaj   +1 more source

Changes in hemoglobin oxidation and band 3 during blood storage impact oxygen sensing and mitochondrial bioenergetic pathways in the human pulmonary arterial endothelial cell model [PDF]

, 2023
Sirsendu Jana, Tigist Kassa, Francine Wood, Wayne Hicks, Abdu I. Alayash   +4 more
openalex   +1 more source

Age-related changes in blood-brain barrier integrity in C57BL/6J mice [PDF]

, 2013
The blood-brain barrier (BBB) is formed by the endothelial cells of the brain microvasculature, which control the molecular traffic between the blood and brain to maintain the neural ...
Romero, I. A., Saffrey, M. J., Wang, C.
core  

Molecular signatures of a TLR4 agonist-adjuvanted HIV-1 vaccine candidate in humans [PDF]

, 2018
Systems biology approaches have recently provided new insights into the mechanisms of action of human vaccines and adjuvants. Here, we investigated early transcriptional signatures induced in whole blood of healthy subjects following vaccination with a ...
Anderson, J, Harandi, AM, Kratochvil, S, McKay, PF, Olafsdottir, TA, Persson, J, Shattock, RJ, östensson, M   +7 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Milieu-adopted in vitro and in vivo differentiation of mesenchymal tissues derived from different adult human CD34-negative progenitor cell clones [PDF]

, 2005
Adult mesenchymal stem cells with multilineage differentiation potentially exist in the bone marrow, but have also been isolated from the peripheral blood.
Huss, R., Hutter, J., Krombach, F., Moosmann, S., Moser, C.   +4 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

NSUN2 relies on ALYREF to regulate Nrf2-mediated oxidative stress and alleviate Dox-induced liver injury

Biology Direct
Background Doxorubicin (Dox) is associated with various liver injuries, limiting its clinical utility. This study investigates whether NSUN2 participates in Dox-induced liver injury and the associated molecular mechanism.
Yingying Huang, Xiao Li, Lin Wei, Shinan Ma, Liming Ma, Yuxin Zan, Xiju He, Yijun Tang, Yan Ding   +8 more
doaj   +1 more source

Renal Findings in Patients with Thalassemia at Abdominal Ultrasound: Should We Still Talk about “Incidentalomas”? Results of a Long-Term Follow-Up

Diagnostics
We retrospectively collected all ultrasound imaging data of our thalassemia patients over a period of 10 years with the aim of assessing the prevalence and the risk factors of renal stones and cysts.
Carmina Fatigati, Antonella Meloni, Silvia Costantini, Anna Spasiano, Flora Ascione, Filippo Cademartiri, Paolo Ricchi   +6 more
doaj   +1 more source