Results 71 to 80 of about 17,492,293 (382)

Tianshengyuan-1 (TSY-1) regulates cellular Telomerase activity by methylation of TERT promoter. [PDF]

open access: yes, 2016
Telomere and Telomerase have recently been explored as anti-aging and anti-cancer drug targets with only limited success. Previously we showed that the Chinese herbal medicine Tianshengyuan-1 (TSY-1), an agent used to treat bone marrow deficiency, has a ...
Chow, Michelle   +9 more
core   +2 more sources

Human Wharton’s jelly-derived mesenchymal stromal cells promote bone formation in immunodeficient mice when administered into a bone microenvironment

open access: yesJournal of Translational Medicine, 2023
Background Wharton’s Jelly (WJ) Mesenchymal Stromal Cells (MSC) have emerged as an attractive allogeneic therapy for a number of indications, except for bone-related conditions requiring new tissue formation.
Raquel Cabrera-Pérez   +5 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Life Is in the Blood [PDF]

open access: yes, 2019
It takes about 60 seconds for all the blood in your body to complete its journey. It travels from your heart to your extremities and returns, there and back again.
Conrad, Jason, Gillen, Alan L.
core   +1 more source

Segmentation of white blood cells and comparison of cell morphology by linear and naïve Bayes classifiers

open access: yesBioMedical Engineering OnLine, 2015
Blood smear microscopic images are routinely investigated by haematologists to diagnose most blood diseases. However, the task is quite tedious and time consuming.
Jaroonrut Prinyakupt   +1 more
semanticscholar   +1 more source

Nervous blood cells [PDF]

open access: yesThe Journal of Cell Biology, 2007
Blood cells feel nervous impulses, reveal findings from Asaf Spiegel, Tsvee Lapidot (Weizmann Institute, Rehovot, Israel), and colleagues. Human blood stem cells express receptors for stress-induced neurotransmitters. Protective white blood cells swarm into the circulation when the body is in alarm mode. Infection, injury, and even anxiety can cause
openaire   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

An epidemiologic study of early biologic effects of benzene in Chinese workers. [PDF]

open access: yes, 1996
Benzene is a recognized hematotoxin and leukemogen, but its mechanisms of action in humans are still uncertain. To provide insight into these processes, we carried out a cross-sectional study of 44 healthy workers currently exposed to benzene (median 8 ...
Bechtold, WE   +20 more
core   +2 more sources

Management of Invasive Infections due to a Rare Arthroconidial Yeast, Saprochaete capitata, in Two Patients with Acute Hematological Malignancies

open access: yesVaccines, 2021
Saprochaete capitata is an arthroconidial yeast, found principally in the environment, even if it belongs also to the normal microbial flora that colonize human subjects.
Francesca Gurrieri   +8 more
doaj   +1 more source

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