Results 111 to 120 of about 21,397 (147)
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Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 2003
Blood coagulation can be initiated by two pathways: the extrinsic pathway, which is triggered by release of tissue factor from the site of injury, and the intrinsic system, which is stimulated by contact with a negatively charged surface. Following initial triggering, a series of serine proteases are sequentially activated, culminating in the formation
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Blood coagulation can be initiated by two pathways: the extrinsic pathway, which is triggered by release of tissue factor from the site of injury, and the intrinsic system, which is stimulated by contact with a negatively charged surface. Following initial triggering, a series of serine proteases are sequentially activated, culminating in the formation
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Cellular and Molecular Life Sciences, 2006
In human patients, blood coagulation disorders often associate with cancer, even in its early stages. Recently, in vitro and in vivo experimental models have shown that oncogene expression, or inactivation of tumour suppressor genes, upregulate genes that control blood coagulation.
BOCCACCIO, Carla, MEDICO, Enzo
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In human patients, blood coagulation disorders often associate with cancer, even in its early stages. Recently, in vitro and in vivo experimental models have shown that oncogene expression, or inactivation of tumour suppressor genes, upregulate genes that control blood coagulation.
BOCCACCIO, Carla, MEDICO, Enzo
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Nature, 1957 Human Blood Coagulation and its Disorders By Dr. Rosemary Biggs and Dr. R. G. Macfarlane. second edition. Pp XXV + 476 + 36 plates. (Oxford: Blackwelf Scientific Publications, 1957.) 42s.net.
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Blood Coagulation and Coagulation Tests
Medical Clinics of North America, 1984The hemostatic mechanism has evolved to provide efficient protection from traumatic blood loss and yet maintain the blood in a fluid state in the circulation as a whole. Recent advances in biochemistry have provided both detailed understanding of hemostasis and clinically useful coagulation assays to exploit this understanding.
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The Lancet, 2000
Under normal circumstances, the coagulation system is balanced in favour of anticoagulation. Thrombin is the key effector enzyme of the clotting cascade. Antagonists of vitamin K inhibit a vitamin-K-dependent post-translational modification of several coagulation proteins, which is required for these proteins to attain a phospholipid-binding ...
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Under normal circumstances, the coagulation system is balanced in favour of anticoagulation. Thrombin is the key effector enzyme of the clotting cascade. Antagonists of vitamin K inhibit a vitamin-K-dependent post-translational modification of several coagulation proteins, which is required for these proteins to attain a phospholipid-binding ...
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Thrombosis and Haemostasis, 1967
SummaryInvestigations were performed on the effects of elinin on blood coagulation. It was found that elinin exerts significant anticoagulant activity. This was demonstrated by an one-stage re calcification test, prothrombin consumption, thromboplastin and thrombin generation.
Giovanni Vulpis +2 more
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SummaryInvestigations were performed on the effects of elinin on blood coagulation. It was found that elinin exerts significant anticoagulant activity. This was demonstrated by an one-stage re calcification test, prothrombin consumption, thromboplastin and thrombin generation.
Giovanni Vulpis +2 more
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Blood Coagulation & Fibrinolysis, 2000
We have used three models to study the process of tissue factor-initiated blood coagulation. These are: synthetic 'plasma' mixtures prepared with the proteins and membranes involved in the reaction and its regulation; mathematical models based on the reaction kinetics, binding constants and stoichiometries of individual procoagulant and inhibitor ...
Saulius Butenas +4 more
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We have used three models to study the process of tissue factor-initiated blood coagulation. These are: synthetic 'plasma' mixtures prepared with the proteins and membranes involved in the reaction and its regulation; mathematical models based on the reaction kinetics, binding constants and stoichiometries of individual procoagulant and inhibitor ...
Saulius Butenas +4 more
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American Journal of Physiology-Legacy Content, 1962
Blood coagulation systems in cyclostome, elasmobranch, and teleost fish were studied and compared. The plasma of all these fish contained a fibrinogen molecule, capable of being clotted by human thrombin, and a prothrombin molecule, capable of being converted into thrombin which could hydrolyze p-tosyl l-arginine methyl ester. The prothrombin activity
Russell F. Doolittle +1 more
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Blood coagulation systems in cyclostome, elasmobranch, and teleost fish were studied and compared. The plasma of all these fish contained a fibrinogen molecule, capable of being clotted by human thrombin, and a prothrombin molecule, capable of being converted into thrombin which could hydrolyze p-tosyl l-arginine methyl ester. The prothrombin activity
Russell F. Doolittle +1 more
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Hemodialysis International, 2001
The endothelium is the principal anti‐thrombotic mechanism, providing a non wettable surface and generating potent vasodilators (nitric oxide and prostacyclin) and clotting inhibitors [thrombomodulin and tissue factor pathway inhibitor (TFPI)]. When the integrity of the endothelium is breached, vasoconstriction occurs through neural and chemical ...
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The endothelium is the principal anti‐thrombotic mechanism, providing a non wettable surface and generating potent vasodilators (nitric oxide and prostacyclin) and clotting inhibitors [thrombomodulin and tissue factor pathway inhibitor (TFPI)]. When the integrity of the endothelium is breached, vasoconstriction occurs through neural and chemical ...
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Blood coagulation in glomerulonephritis
International Urology and Nephrology, 1986Different parameters of coagulation were studied in 71 patients with glomerulonephritis. In comparison with normal subjects they had lower platelet counts, lower adhesion index and decreased aggregation, decreased partial thromboplastin time (46.4 per cent of patients), increased reptilase time (47.8 per cent) and other disorders. Plasma fibrin monomer
R Robeva, V Genova, N Belovezhdov
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