Results 21 to 30 of about 5,111,387 (310)

Effect of MSCs and MSC-Derived Extracellular Vesicles on Human Blood Coagulation

open access: yesCells, 2019
Mesenchymal stem cells (MSCs) have emerged as a potent therapeutic tool for the treatment of a number of pathologies, including immune pathologies. However, unwelcome effects of MSCs on blood coagulation have been reported, motivating us to explore the ...
D. Silachev   +16 more
semanticscholar   +1 more source

Recurrent Venous Thromboembolism: What Is the Risk and How to Prevent It

open access: yesScientifica, 2012
Venous thromboembolism (VTE) that includes deep vein thrombosis and/or pulmonary embolism is a frequent, severe, and potentially lethal disease. After a first episode, VTE has a strong tendency to recur.
Gualtiero Palareti
doaj   +1 more source

The international, prospective Glanzmann Thrombasthenia Registry: treatment and outcomes in surgical intervention

open access: yesHaematologica, 2015
Standard treatment for Glanzmann thrombasthenia, a severe inherited bleeding disorder, is platelet transfusion. Recombinant factor VIIa is reported to be effective in Glanzmann thrombasthenia with platelet antibodies and/or refractoriness to platelet ...
Man-Chiu Poon   +5 more
doaj   +1 more source

Technology Advancements in Blood Coagulation Measurements for Point-of-Care Diagnostic Testing

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
In recent years, blood coagulation monitoring has become crucial to diagnosing causes of hemorrhages, developing anticoagulant drugs, assessing bleeding risk in extensive surgery procedures and dialysis, and investigating the efficacy of hemostatic ...
Mohammad Mohammadi Aria   +2 more
semanticscholar   +1 more source

Platelet biomechanics, platelet bioenergetics, and applications to clinical practice and translational research

open access: yesPlatelets, 2018
The purpose of this review is to explore the relationship between platelet bioenergetics and biomechanics and how this relationship affects the clinical interpretation of platelet function devices. Recent experimental and technological advances highlight
Mitchell J. George   +6 more
doaj   +1 more source

The International Prospective Glanzmann Thrombasthenia Registry: Pediatric Treatment and Outcomes

open access: yesTH Open, 2019
Background Standard treatment for Glanzmann thrombasthenia (GT), a severe inherited bleeding disorder, is platelet transfusion. Recombinant activated factor VII (rFVIIa) is reported to be effective in GT with platelet antibodies and/or refractoriness to ...
Rainer B. Zotz   +3 more
doaj   +1 more source

Role of the blood coagulation cascade in hepatic fibrosis.

open access: yesAmerican Journal of Physiology - Gastrointestinal and Liver Physiology, 2018
Liver is the primary source of numerous proteins that are critical for normal function of the blood coagulation cascade. Because of this, diseases of the liver, particularly when affiliated with severe complications like cirrhosis, are associated with ...
Asmita Pant, A. Kopec, J. Luyendyk
semanticscholar   +1 more source

The international, prospective Glanzmann Thrombasthenia Registry: treatment modalities and outcomes of non-surgical bleeding episodes in patients with Glanzmann thrombasthenia

open access: yesHaematologica, 2015
Standard treatment for Glanzmann thrombasthenia is platelet transfusion. Recombinant activated factor VII has been shown to be successful in patients with Glanzmann thrombasthenia with platelet antibodies or who are refractory to platelet transfusions ...
Giovanni Di Minno   +5 more
doaj   +1 more source

Blood Coagulation Response and Bacterial Adhesion to Biomimetic Polyurethane Biomaterials Prepared with Surface Texturing and Nitric Oxide Release

open access: yesActa Biomaterialia, 2018
A dual functional polyurethane (PU) film that mimics aspects of blood vessel inner surfaces by combining surface texturing and nitric oxide (NO) release was fabricated through a soft lithography two-stage replication process. The fabrication of submicron
Li-Chong Xu, M. Meyerhoff, C. Siedlecki
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy