Results 251 to 260 of about 1,019,042 (345)

O‐GalNAc Glycosylation Activates MBL‐Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis

open access: yesAdvanced Science, EarlyView.
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen   +24 more
wiley   +1 more source

Acute myeloid leukemia: A rare cause of acquired isolated factor VII deficiency. [PDF]

open access: yesLeuk Res Rep
Mlayah Z   +5 more
europepmc   +1 more source

A Wearable In‐Pad Diagnostic for the Detection of Disease Biomarkers in Menstruation Blood

open access: yesAdvanced Science, EarlyView.
MenstruAI integrates a paper‐based biosensor into sanitary pads to detect biomarkers in menstrual blood, enabling accessible, lab‐free diagnostics health. The platform supports early disease detection, especially in underserved communities, while challenging menstrual stigma and opening pathways for scalable, inclusive, and sustainable population ...
Lucas Dosnon   +3 more
wiley   +1 more source

YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li   +8 more
wiley   +1 more source

Mechanism and modification of rejection of heterografts between divergent species. [PDF]

open access: yes, 1970
Amemiya, H   +9 more
core  

Microfluidic Biochip‐Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis

open access: yesAdvanced Science, EarlyView.
This study develops a diagnostic platform for early detection of esophageal squamous cell carcinoma (ESCC) by integrating a barcode immunoassay biochip with machine learning. The biochip captures and analyzes small extracellular vesicle proteins from serum samples, identifying nine biomarkers linked to ESCC.
Xue Zhang   +14 more
wiley   +1 more source

Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials. [PDF]

open access: yesFront Cardiovasc Med
Große-Berkenbusch K   +8 more
europepmc   +1 more source

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