Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen+24 more
wiley +1 more source
Acute myeloid leukemia: A rare cause of acquired isolated factor VII deficiency. [PDF]
Mlayah Z+5 more
europepmc +1 more source
A Wearable In‐Pad Diagnostic for the Detection of Disease Biomarkers in Menstruation Blood
MenstruAI integrates a paper‐based biosensor into sanitary pads to detect biomarkers in menstrual blood, enabling accessible, lab‐free diagnostics health. The platform supports early disease detection, especially in underserved communities, while challenging menstrual stigma and opening pathways for scalable, inclusive, and sustainable population ...
Lucas Dosnon+3 more
wiley +1 more source
Perioperative Management of Single Lung Transplantation for a Chronic Obstructive Lung Disease Patient with Congenital Alpha<sub>2</sub>-Plasmin Inhibitor Deficiency. [PDF]
Miyahara S+6 more
europepmc +1 more source
YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li+8 more
wiley +1 more source
Coagulation Status Assessment in Dogs with Chronic Enteropathy Using Viscoelastic Point-of-Care Coagulation Monitor. [PDF]
Marín Lucas MJ, Sparks T, Rosa C.
europepmc +1 more source
Mechanism and modification of rejection of heterografts between divergent species. [PDF]
Amemiya, H+9 more
core
This study develops a diagnostic platform for early detection of esophageal squamous cell carcinoma (ESCC) by integrating a barcode immunoassay biochip with machine learning. The biochip captures and analyzes small extracellular vesicle proteins from serum samples, identifying nine biomarkers linked to ESCC.
Xue Zhang+14 more
wiley +1 more source
Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials. [PDF]
Große-Berkenbusch K+8 more
europepmc +1 more source
Thrombelastography Should Be Included in the Algorithm for the Management of Postpartum Hemorrhage [PDF]
Frietsch, Thomas+3 more
core +2 more sources