Results 21 to 30 of about 139,921 (264)
Thromboelastometry profile in critically ill patients: A single-center, retrospective, observational study. [PDF]
PLoS ONE, 2018 Transfusion therapy is associated with increased morbidity, mortality and costs. Conventional coagulation tests (CCT) are weak bleeding predictors, poorly reflecting coagulation in vivo.
Tomaz Crochemore +11 more
doaj +1 more source
Individualized Management of Coagulopathy in Patients with End-Stage Liver Disease
Diagnostics, 2022 Over the last decades, individualized approaches and a better understanding of coagulopathy complexity in end-stage liver disease (ESLD) patients has evolved.
Tina Tomić Mahečić +8 more
doaj +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2020 Background and Objective: One of the health indices in human is normality of the number and size of blood cells. The purpose of this study was to screen for bleeding and coagulation disorders among the patients in oral medicine department of Yazd dental ...
Hoda Farmanara, Hakimeh Ahadian
doaj
The Organophosphate Paraoxon and Its Antidote Obidoxime Inhibit Thrombin Activity and Affect Coagulation In Vitro. [PDF]
PLoS ONE, 2016 Organophosphates (OPs) are potentially able to affect serine proteases by reacting with their active site. The potential effects of OPs on coagulation factors such as thrombin and on coagulation tests have been only partially characterized and potential ...
Valery Golderman +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Early and individualized goal-directed therapy for trauma-induced coagulopathy
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2012 Severe trauma-related bleeding is associated with high mortality. Standard coagulation tests provide limited information on the underlying coagulation disorder.
Schöchl Herbert +4 more
doaj +1 more source
Viscoelastic Tests in the Evaluation of Haemostasis Disturbances in SARS-CoV2 Infection
Acta Médica Portuguesa, 2021 COVID-19 associated coagulopathy is a dysfunction of severe SARS-CoV-2 infection, characterized by significantly increased fibrinogen, D-dimer and C reactive protein and normal to near-normal prothrombin time, activated partial thromboplastin time and ...
Anabela Rodrigues +4 more
doaj +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
Research and Practice in Thrombosis and HaemostasisBackground: Severe exercise performed over longer duration can involve multiple prothrombotic alterations in blood coagulation markers. Standard coagulation tests are not robust in identifying hyper- or hypocoagulability due to indirect determination of ...
Wolfgang Schobersberger +11 more
doaj +1 more source