Results 41 to 50 of about 1,143,596 (312)

Assessment of blood cultures and antibiotic susceptibility testing for bacterial sepsis diagnosis and utilization of results by clinicians in Benin: A qualitative study

Frontiers in Public Health, 2023
ObjectivesWe assessed the current status of blood culture and antibiotic susceptibility testing (AST) practices in clinical laboratories in Benin, and how the laboratory results are used by physicians to prescribe antibiotics.MethodsThe qualitative study
Brice Boris Legba, Victorien Dougnon, Hornel Koudokpon, Sointu Mero, Sointu Mero, Riku Elovainio, Riku Elovainio, Matti Parry, Matti Parry, Honoré Bankole, Kaisa Haukka, Kaisa Haukka   +11 more
doaj   +1 more source

Granulocyte-Macrophage-Colony-Stimulating-Factor Combined with Prostaglandin E1 Create Dendritic Cells of Leukemic Origin from AML Patients’ Whole Blood and Whole Bone Marrow That Mediate Antileukemic Processes after Mixed Lymphocyte Culture [PDF]

, 2023
Marianne Unterfrauner, Hazal Aslan Rejeski, Anne Hartz, Sophia Bohlscheid, Tobias Baudrexler, Xiaojia Feng, Elias Rackl, Lin Li, Andreas Rank, Giuliano Filippini Velázquez, Christoph Schmid, Jörg Schmohl, Peter Bojko, Helga Schmetzer   +13 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Pattern of Respiratory Problems in Neonates in a Level III Neonatal Care Unit with Special Reference to Pneumonia [PDF]

Indian Journal of Neonatal Medicine and Research, 2016
Introduction: Respiratory distress constitutes one of the commonest cause of morbidity and mortality in the neonatal period. It is more commonly encountered within the first 48-72 hours of life.
Aukifa Khamim Sabibahul Islam, Reeta Bora, Nibedita Paul, Sutharson Ramasamy   +3 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Bacteriologic Antibiography Outline of Isolates from Blood Culture at Tertiary Center

Journal of Pure and Applied Microbiology, 2020
Bacteria found in blood circulation either consistently intermittently are commination to every organs of body. These infections can affect life and death.
Dhruba Hari Chandi, Praful Patil, Smita Damke, Silpi Basak, Rangaiahagari Ashok   +4 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A CASE OF MYCOTIC SEPSIS DUE TO TRICHOSPORON COREMIIFORME IN A TRAUMA PATIENT IN MHAT-SHUMEN

Problems of Infectious and Parasitic Diseases
Trichosporon spp. are yeast-like fungi,a rare cause of mycotic sepsis. We share a case report of a thirty-three year old man with polytrauma after a car accident, who died after a long hospitalization and treatment in intensive care unit.
Stanislava Voycheva, Emilia Bozova, Ivva Philipova, Lyubomira Boyanova   +3 more
doaj   +1 more source

Blood culture contamination rates at different level healthcare institutions in the Western Cape, South Africa

Southern African Journal of Infectious Diseases, 2020
Sterile blood culture (BC) collection procedures are important to prevent the consequences of contamination, namely, prolonged patient hospitalisation, unnecessary antimicrobial exposure and an increase in hospital costs.
Christoffel J. Opperman, Banyana Baloyi, Sipho Dlamini, Nazlee Samodien   +3 more
doaj   +1 more source