Results 51 to 60 of about 2,362,330 (266)

Clinical and Laboratory Potential Predictors of Blood Culture Positivity in Under Five Children with Clinically Severe Pneumonia - Khartoum -Sudan [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Blood culture is necessary for appropriate management of clinically severe pneumonia in children under five years of age. However, in limited resource countries it might be unduly costly and waste of valuable time because of the high ...
Karimeldin Mohamed Ali Salih, El-Fatih El-Samani, Jalal Ali Bilal, Widad Eldouch, Salah Ahmed Ibrahim   +4 more
doaj   +1 more source

Comparison of whole blood, serum, and plasma for early detection of candidemia by multiplex-tandem PCR [PDF]

, 2010
We applied multiplex-tandem PCR (MT-PCR) to 255 EDTA whole-blood specimens, 29 serum specimens, and 24 plasma specimens from 109 patients with Candida bloodstream infection (candidemia) to determine whether a diagnosis could be expedited in comparison ...
Lau, Anna, Halliday, Catriona, Chen, Sharon C.-A., Playford, E. Geoffrey, Stanley, Keith, Sorrell, Tania C.   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The potential utility of real-time PCR of the 16S-rRNA gene in the diagnosis of neonatal sepsis

The Turkish Journal of Pediatrics, 2019
The purpose of this study was to evaluate the efficacy of real-time polymerase chain reaction (PCR) of the 16S rRNA gene in diagnosis of neonatal sepsis and compare it with conventional blood culture.
Kenan İstanbullu, Nilgün Köksal, Merih Çetinkaya, Hilal Özkan, Tahsin Yakut, Mutlu Karkucak, Haldun Doğan   +6 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Culture Positive Brucella Endocarditis in a Case of Baloon Mitral Valvotomy [PDF]

, 2011
Brucella endocarditis is a rare condition which occurs as a focal complication in chronic brucellosis cases. We report a rare brucella endocarditis case in a RVHD patient. A 26 years old male was admitted with fever on off for almost one year.
Aundhkar, S, Ghorpade, MV, Pawar, SK
core  

Inactivation of Plasmodium falciparum in whole blood by riboflavin plus irradiation.

, 2013
BACKGROUND: Malaria parasites are frequently transmitted by unscreened blood transfusions in Africa. Pathogen reduction methods in whole blood would thus greatly improve blood safety.
Allain, Jean-Pierre, Atwal, Sharan, Dinko, Bismarck, El Chaar, Mira, Freimanis, Graham L, Sutherland, Colin J   +5 more
core   +1 more source

Correlation between mass and volume of collected blood with positivity of blood cultures [PDF]

, 2015
Background The collection of blood cultures is an extremely important method in the management of patients with suspected infection. Microbiology laboratories should monitor blood culture collection.
da Silva Victor, Elivane, da Silva, Patrícia Candido, de Moura, Natália Ariede, dos Santos, Maura Cristina, Edmond, Michael B., Marra, Alexandre Rodrigues, Neves, Lariessa, Pasternak, Jacyr, Pavão dos Santos, Oscar Fernando, Sampaio Camargo, Thiago Zinsly, Valle Martino, Marines Dalla, Zulin, Flávia   +11 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source