Results 21 to 30 of about 356,868 (313)

Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells

eLife, 2020
Acute Myeloid Leukemia (AML) is an aggressive hematological malignancy with abnormal progenitor self-renewal and defective white blood cell differentiation.
Ana Filipa Domingues, Rashmi Kulkarni, George Giotopoulos, Shikha Gupta, Laura Vinnenberg, Liliana Arede, Elena Foerner, Mitra Khalili, Rita Romano Adao, Ayona Johns, Shengjiang Tan, Keti Zeka, Brian J Huntly, Sudhakaran Prabakaran, Cristina Pina   +14 more
doaj   +1 more source

Blood donors

International journal of health sciences, 2022
Evaluation of TTI (transfusion transmitted infections) are essential for assessing the safety of blood supply and monitoring the efficacy of currently employed screening procedures. Objective: To assess the prevalence of HBV, HCV and HIV among replacement donors and voluntary donor in association with the Kuppuswamy’s socioeconomic status. Material and
Jyotsana Khattri, Madhvi Sanwelka, Shyamoli Dutta, Seema Awasthi   +3 more
openaire   +1 more source

Retrospective evaluation of unexpected events during collection of blood donations performed with and without sedation in cats (2010-2013) [PDF]

, 2017
Objectives – To review the feline blood donor records from a single center and to compare blood donations that were performed with and without sedation.Design – Retrospective observational study from 2010 to 2013.Setting – University teaching hospital ...
Barfield, Carney, DeLuca, Helm, Iazbik, Killos, Klein, Kohn, McCullough, Rodan, Spada, Trouern-Trend, Walton, Wardrop, Weingart, Weingart   +15 more
core   +3 more sources

AMBIGUITY OF LOCI DURING HLA-TYPING ON SSO TECHNOLOGY AND ATTEMPT TO RESOLVE THEM

Вестник трансплантологии и искусственных органов, 2010
Sequence specific oligonucleotides typing was used to identify human leukocyte antigen (HLA)-A, B, DRB1 alleles from 705 recruited volunteers with Volga Federal District for unrelated hematopoietic stem cell registry and 155 of their number at locus HLA ...
M. A. Loginova, I. V. Paramonov, N. P. Trofimova   +2 more
doaj   +1 more source

Pooled human bone marrow-derived mesenchymal stromal cells with defined trophic factors cargo promote dermal wound healing in diabetic rats by improved vascularization and dynamic recruitment of M2-like macrophages

Frontiers in Immunology, 2022
Human Mesenchymal Stromal Cells (hMSCs) are a promising source for cell-based therapies. Yet, transition to phase III and IV clinical trials is remarkably slow.
Hélène Willer, Hélène Willer, Gabriele Spohn, Kimberly Morgenroth, Corinna Thielemann, Susanne Elvers-Hornung, Peter Bugert, Bruno Delorme, Melanie Giesen, Thomas Schmitz-Rixen, Erhard Seifried, Christiane Pfarrer, Richard Schäfer, Richard Schäfer, Richard Schäfer, Karen Bieback, Karen Bieback, Karen Bieback   +17 more
doaj   +1 more source

Donor selection for allogenic hemopoietic stem cell transplantation: clinical and ethical considerations [PDF]

, 2017
Allogenic hematopoietic progenitor cell transplantation (allo-HSCT) is an established treatment for many diseases. Stem cells may be obtained from different sources: mobilized peripheral blood stem cells, bone marrow, and umbilical cord blood.
La Russa, Raffaele, Liso, Arcangelo, Pascale, Natascha, Riezzo, Irene, Salerno, Monica, Turillazzi, Emanuela   +5 more
core   +4 more sources

THE USE OF NEW REAGENT KITS FOR DETECTION AND DESCRIPTION OF ADDITIONAL ALLELES

Вестник трансплантологии и искусственных органов, 2011
During the screening typing of recruited volunteers with Volga Federal District for unrelated hematopoietic stem cell registry on the loci (HLA)-A, B, DRB1, DRB345 in sample No 1758 identified a new allele at locus A.
M. A. Loginova, N. P. Trophimova, I. V. Paramonov   +2 more
doaj   +1 more source

Parvovirus B19 DNA detectable in hearts of patients with dilated cardiomyopathy, but absent or inactive in blood

ESC Heart Failure, 2021
Aims Parvovirus B19 (B19V) is often assumed to be a cause of dilated cardiomyopathy (DCM), based on the quantification of B19V DNA in endomyocardial biopsies (EMB).
Anne Russcher, Job Verdonschot, Marijke W.A. Molenaar‐de Backer, Stephane R.B. Heymans, Aloys C.M. Kroes, Hans L. Zaaijer   +5 more
doaj   +1 more source

Whole-blood sorting, enrichment and in situ immunolabeling of cellular subsets using acoustic microstreaming [PDF]

, 2018
Analyzing undiluted whole human blood is a challenge due to its complex composition of hematopoietic cellular populations, nucleic acids, metabolites, and proteins. We present a novel multi-functional microfluidic acoustic streaming platform that enables
Garg, Neha, Lee, Abraham P, Liu, Robin, Liu, Vick, Nelson, Edward L, Westerhof, Trisha M   +5 more
core   +1 more source

Human mesenchymal stromal cells inhibit platelet activation and aggregation involving CD73-converted adenosine

Stem Cell Research & Therapy, 2018
Background Mesenchymal stromal cells (MSCs) are promising cell therapy candidates. Clinical application is considered safe. However, minor side effects have included thromboembolism and instant blood-mediated inflammatory reactions suggesting an effect ...
P. Netsch, S. Elvers-Hornung, S. Uhlig, H. Klüter, V. Huck, F. Kirschhöfer, G. Brenner-Weiß, K. Janetzko, H. Solz, P. Wuchter, P. Bugert, K. Bieback   +11 more
doaj   +1 more source