Results 91 to 100 of about 5,195,311 (386)

Techniques used for the screening of hemoglobin levels in blood donors: current insights and future directions

Journal of Blood Medicine, 2017
Blood donor hemoglobin (Hb) estimation is an important donation test that is performed prior to blood donation. It serves the dual purpose of protecting the donors’ health against anemia and ensuring good quality of blood components, which has an ...
R. Chaudhary, Anju Dubey, Atul Sonker
semanticscholar   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Frequencies of polymorphisms of the Rh, Kell, Kidd, Duffy and Diego systems of Santa Catarina, Southern Brazil

Revista Brasileira de Hematologia e Hemoterapia
BACKGROUND: Red blood cell genes are highly polymorphic with the distribution of alleles varying between different populations and ethnic groups. The objective of this study was to investigate gene polymorphisms of blood groups in the state of Santa ...
Daiane Cobianchi Costa, Alessandra Arruda Schinaider, Thais Mattos Santos, Everaldo José Schörner, Daniel Simon, Sharbel Weidner Maluf, Ana Carolina Rabello de Moraes, Maria Claudia Silva Silva   +7 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Strategies for reducing the risk of transfusion-transmitted leishmaniasis in an area endemic for Leishmania infantum: a patient- and donor-targeted approach [PDF]

, 2017
Background. In the Balearic Islands, as in other areas of the Mediterranean basin, there is a significant proportion of asymptomatic Leishmania (L.) infantum-infected blood donors, who may represent an important threat to transfusion safety. The Balearic
Alcover Amengual, Maria Magdalena, Berenguer, Diana, Cancino Faure, María Beatriz, Fisa Saladrigas, Roser, Gascó, Joan, Girona-Llobera, Enrique, Guillen, Carmen, Iniesta González, Laura, Jimenez-Marco, Teresa, Mascaró, Martín, Pujol Brugués, Alba, Riera Lizandra, Ma. Cristina, Serra, Teresa, Tomás Pérez, Míriam   +13 more
core   +1 more source

Seroprevalence and Incidence of hepatitis E in Blood Donors in Upper Austria

PLoS ONE, 2015
Background In recent years various studies showed, that hepatitis E virus (HEV) is a growing public health problem in many developed countries. Therefore, HEV infections might bear a transmission risk by blood transfusions.
C. Fischer, M. Hofmann, M. Danzer, K. Hofer, J. Kaar, C. Gabriel   +5 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Correlation of heavy metals and theirs impact to epidemiological survey in the miners blood donors and other human population [PDF]

, 2011
Introduction: Miners who are blood donors, and work in mines for lead-zinc ores are constantly exposed to heavy metals (lead, zinc and cadmium) and this aspect is expected to increase or decrease many hematological parameters.
Kamcev, Nikola, Kamceva, Gordana, Panov, Zoran, Velickova, Nevenka   +3 more
core  

Bartonella spp. Bacteremia in Blood Donors from Campinas, Brazil

PLoS Neglected Tropical Diseases, 2015
Bartonella species are blood-borne, re-emerging organisms, capable of causing prolonged infection with diverse disease manifestations, from asymptomatic bacteremia to chronic debilitating disease and death.
L. Pitassi, Pedro Paulo Vissotto de Paiva Diniz, D. Scorpio, M. Drummond, B. G. Lania, M. L. Barjas-Castro, R. Gilioli, S. Colombo, S. Sowy, E. Breitschwerdt, W. Nicholson, P. Velho   +11 more
semanticscholar   +1 more source