Results 111 to 120 of about 2,806,860 (258)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The prevalence of HIV among blood donors at Juba Teaching Hospital Blood Bank, South Sudan

, 2014
Objectives The aim of this study is to determine the prevalence of HIV among blood donors in Juba Teaching Hospital Blood Bank, South Sudan in 2013.
Rose P Gore, Kenneth L L Sube, Salvador Jaja, Isaac W Abraham, Richard L Loro, Emmanuel O Lino, Opiaka A Seriano, Loboro J Alex, Kwoji R Jack[, Oromo F Seriano, Samuel N Wani   +10 more
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Blood Donors Deferral- Causes

Journal of Rawalpindi Medical College, 2013
Background: To determine the frequency and reasons of rejection of blood donors. Methods: In this descriptive study the evaluation of blood donors was carried out for jaundice,anaemia, malaria, ulcers, diabetes, syphilis, tuberculosis, rheumatic fever ...
Samina Tufail
doaj  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Sociodemographic and Behavioral Characteristics of HIV Antibody-Positive Blood Donors

, 1988
This paper describes the sociodemographic and behavioral characteristics of 173 blood donors who were confirmed by Western blot tests to have antibodies to human immunodeficiency virus (HIV), the etiologic agent for acquired immunodeficiency syndrome ...
Cleary, Paul D.,, Cleary, Paul D.
core   +1 more source

Dietary characteristics associated with hemoglobin and anemia among prospective first-time voluntary blood donors in Accra, Ghana

BMC Nutrition
Background Optimal dietary intake supports adequate hemoglobin (Hb) levels for blood donation. However, little is known about the dietary characteristics of prospective first-time voluntary blood donors (VBDs) in Ghana and their associations with Hb and ...
Salmana Mehmood, Susan Telke, Edeghonghon Olayemi, Caitlin Ward, Lucy Asamoah-Akuoko, Bernard Appiah, Alfred Edwin Yawson, Tara Tancred, Amma Anima Benneh-Akwasi Kuma, Reena Ametorwo, Frank Ofori, Philip Baba Adongo, Jerry Daneku, Isaac Danso, Abigail Nana Afua Amegadoe, Catherine Segbefia, Cavan Reilly, Yvonne Dei-Adomakoh, Seth Adu-Afarwuah, the BLOODSAFE Ghana Investigators   +19 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The prevalence of HIV infection among blood donors: a systematic review and meta-analysis

Blood recipients, particularly frequent receivers, are at high-risk of receiving human immunodeficiency virus (HIV), and no current serologic tests eliminate this transmission risk.
Alireza Ebrahimi, Sahar Hosseini, Soheil Ashkani-Esfahani, Leila Kasraian, Rohan Bhimani   +4 more
core   +1 more source

Results of Serologic Screening Tests from Blood Donors at One University Hospital-based Blood Bank during 2006∼2008 [PDF]

, 2009
Background: Any data on the prevalence of the infectious diseases of blood donors at a university hospital-based blood bank is not available. We aimed to analyze the seroincidence of screening tests from blood donors at a university hospital-based blood ...
김현옥, 김현숙
core