Results 111 to 120 of about 340,510 (266)

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Investigation of the Reasons for the Non-Return of Lapsed Blood Donors: A Qualitative Study. [PDF]

Health Sci Rep
Javadzadeh Shahshahani H, Fattahi Ardakani M, Amiri F, Kazemi S, Heydari S, Zareipour M, Meybody SMA, Rointan H, Vaziri M.   +8 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A novel reagent for the screening of Immunoglobulin A-deficient blood donors. [PDF]

Vox Sang
Watanabe-Okochi N, Sato A, Okuyama A, Tomiyoshi G, Suzuki Y, Watanabe Y, Anazawa M, Shimoyamada T, Takahashi D, Onodera T, Uchikawa M, Miyata S.   +11 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Dengue Seroprevalence Among Blood Donors in the Lazio Region (Italy): Is There an Iceberg Beneath the Surface? [PDF]

J Med Virol
Spaziante M, Rosa L, Colavita F, Mussetto I, De Carli G, Vantaggio V, Agresta A, Coen S, Cammisa S, D'Abramo A, Maffongelli G, Vaglio S, Iaboni S, Casorelli I, Mele L, Teofili L, Scognamiglio P, Siddu A, Nicastri E, Maggi F, Girardi E, ARBODONORS Working Group, Vairo F.   +22 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Related Factors of Syphilis Positive Rate in Blood Donors During the COVID-19 Epidemic

International Journal of General Medicine
Song-Xing Wang,1,2,* Li-Yan Sun,3,* Qiong Yu,2 Ran Li,4 Yun-Ping Xu,3 Jin-Feng Zeng4 1Clinical Laboratory, The Third People’s Hospital of Longgang District, Shenzhen, People’s Republic of China; 2Quality Control Department, Shenzhen Blood Center,
Wang SX, Sun LY, Yu Q, Li R, Xu YP, Zeng JF   +5 more
doaj  

Western Equine Encephalitis Virus in Blood Donors during Outbreak, Argentina, 2023-2024. [PDF]

Emerg Infect Dis
Blanco S, Frutos MC, Brenot K, Bustamante AG, Carrizo LH, Gallego SV.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source