Results 131 to 140 of about 366,746 (310)

Efforts to link HIV-positive and high-risk blood donors to HIV testing, and treatment services, Mozambique, 2019–2020

open access: yesScientific Reports
Mozambique’s National Blood Transfusion Services (NBTS) is tasked with providing safe and available blood but also conducting systematic screening of at-risk potential donors, notifying seropositive blood donors, and linking them to HIV care and ...
Udhayashankar Kanagasabai   +12 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Assessing Knowledge, Public Awareness, and Confidence Assurance of Apheresis Donors among Blood Bank Donors in Tobruk, Libya.

open access: yesTobruk University Journal of Medical Sciences
Background: Blood donation is a critical component of healthcare, and apheresis has emerged as an advanced technique for collecting specific blood components, such as platelets, plasma, and red blood cells. Despite its advantages, apheresis remains less
Alkadafe Agelah, Hanan Mahdi
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Results of Serologic Screening Tests from Blood Donors at One University Hospital-based Blood Bank during 2006∼2008 [PDF]

open access: yes, 2009
Background: Any data on the prevalence of the infectious diseases of blood donors at a university hospital-based blood bank is not available. We aimed to analyze the seroincidence of screening tests from blood donors at a university hospital-based blood ...
김현옥, 김현숙
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Expert consensus on adjustment of pre-donation blood pressure screening requirements for blood donor population in China [PDF]

open access: yes
Standards for blood donors selection are established to ensure the safety of both donors and recipients, as well as the quality of blood products and an adequate blood supply.
Expert Panel on Blood Pressure Screening Strategies for Blood Donor Selection
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Population characteristics and trends among HIV-positive voluntary blood donors in Guangzhou from 2012 to 2022

open access: yesZhongguo shuxue zazhi
Objective To investigate the population data of human immunodeficiency virus (HIV) infections among voluntary blood donors in Guangzhou between 2012 and 2022, and analyze its characteristics and trends, so as to provide valuable data for formulating ...
Ye TIAN   +6 more
doaj   +1 more source

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