Results 151 to 160 of about 2,806,860 (258)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Dengue Seroprevalence Among Blood Donors in the Lazio Region (Italy): Is There an Iceberg Beneath the Surface? [PDF]

J Med Virol
Spaziante M, Rosa L, Colavita F, Mussetto I, De Carli G, Vantaggio V, Agresta A, Coen S, Cammisa S, D'Abramo A, Maffongelli G, Vaglio S, Iaboni S, Casorelli I, Mele L, Teofili L, Scognamiglio P, Siddu A, Nicastri E, Maggi F, Girardi E, ARBODONORS Working Group, Vairo F.   +22 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Prevalence of Serologic Weak D Phenotype in Iranian Blood Donors: A Nationwide Retrospective Cross-Sectional Study. [PDF]

Health Sci Rep
Sadeghi-Bojd Y, Alhosayni NSR, Mirzaeyan F, Mohammadali F, Oodi A.   +4 more
europepmc   +1 more source

Chagas disease in Canadian blood donors: 15 years of selective testing. [PDF]

Vox Sang
O'Brien SF, Goldman M, Lewin A, Uzicanin S, Fan W, Drews SJ.   +5 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Western Equine Encephalitis Virus in Blood Donors during Outbreak, Argentina, 2023-2024. [PDF]

Emerg Infect Dis
Blanco S, Frutos MC, Brenot K, Bustamante AG, Carrizo LH, Gallego SV.   +5 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Pre-exposure prophylaxis use in blood donors in England. [PDF]

Vox Sang
Debrah J, Reynolds C, Maddox V, Secret S, Baklan H, Amara A, Else L, Simmonds P, Brailsford SR, Khoo S, Harvala H.   +10 more
europepmc   +1 more source