Results 171 to 180 of about 366,746 (310)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Seroprevalence of Hepatitis-E infection in healthy blood donors in an endemic country. [PDF]

Pak J Med Sci
Kamani L, Rahat A, Anwar S.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The Distributions of Duffy Antigens and Phenotypes Among Blood Donors in King Abdulaziz Medical City-Western Region, Saudi Arabia: A Cross-Sectional Study [PDF]

Amr J Halawani,1 Sahal A Jamalallail,2 Abdullah M Algarni,2 Mohammad H Alsomali,2 Sulaiman S Alabsi,2 Ammar M Sahl,2 Afnan T Kumosani,2 Saja M Asali,2 Alaa H Qudayr,2 Banan A Mallah,2 Ahmed A Mari,2 Hiam O Mulla,3– 5 Ali H Alhussain Snr,6 Sarah M Alahwal,
Algarni AM, Alomari FD, Alabsi SS, Mari AA, Sahl AM, Qudayr AH, Asali SM, Alhussain Snr AH, Mulla HO, Halawani AJ, Kumosani AT, Alahwal SM, Mallah BA, Jamalallail SA, Alsomali MH   +14 more
core   +1 more source

Reentry of voluntary blood donors in Chongqing, China (2022-2024): a retrospective single-center analysis. [PDF]

Front Med (Lausanne)
Qin W, Hu T, Gan Y, Tian Y, Zhu X.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Decision and non-decision making among blood donors and non-blood donors towards voluntary blood donation

Muller Journal of Medical Sciences and Research, 2015
Umakanth Siromani, Thankamony Thasian, Rita Isaac, Kurusilappattu Gurupachai Selvaraj, Dolly Daniel, Joy John Mammen, Sukesh Chandra Nair   +6 more
doaj   +1 more source

Evaluation of non-invasive hemoglobin measurement in blood donors at a tertiary care hospital, Bangkok, Thailand. [PDF]

PLoS One
Dangwilailert R, Lekmak S, Promlee D, Pongkunakorn T, Permpikul P.   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source