Results 121 to 130 of about 2,806,860 (258)
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Blood-borne viral infections among blood, organ and tissue donors [PDF]
, 2016 The article presents an actual information on the detection rate of blood-borne viral infections (BBVI) among blood donors, potential organ and tissue donors in Russia and other countries. The causes of differences in BBVI prevalence between blood donors
M. Sh. Khubutiya +3 more
core
Tobruk University Journal of Medical SciencesBackground: Blood donation is a critical component of healthcare, and apheresis has emerged as an advanced technique for collecting specific blood components, such as platelets, plasma, and red blood cells. Despite its advantages, apheresis remains less
Alkadafe Agelah, Hanan Mahdi
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Blood donor selection; guidelines on assessing donor suitability for blood donation [PDF]
The WHO guidelines on assessing donor suitability for blood donation have been developed to assist blood transfusion services in countries that are establishing or strengthening national systems for the selection of blood donors.
core
Vasovagal reactions in blood donors during or immediately after blood donation
, 2020 SUMMARY. The aim of the study was to estimate the type, incidence and causes of donor adverse reactions during and after blood donation in a Greek Blood Bank, where medical staff is responsible for donor selection.
E K Zervou +6 more
core
Scientific ReportsMozambique’s National Blood Transfusion Services (NBTS) is tasked with providing safe and available blood but also conducting systematic screening of at-risk potential donors, notifying seropositive blood donors, and linking them to HIV care and ...
Udhayashankar Kanagasabai +12 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Recoding the gift relationship: views on introducing genomic testing to blood donation
This study examines how the institutional context informs the ways in which healthy recipients relate to genomic information. Through focus group data, it considers the trend of blood collection agencies (BCA) moving to extend donor genotyping.
Vera Raivola +5 more
core +1 more source