Results 21 to 30 of about 10,661,666 (408)

TIGIT-positive circulating follicular helper T cells display robust B-cell help functions: potential role in sickle cell alloimmunization

Haematologica, 2015
T follicular helper cells are the main CD4+ T cells specialized in supporting B-cell responses, but their role in driving transfusion-associated alloimmunization is not fully characterized.
Emmanuelle Godefroy, Hui Zhong, Petra Pham, David Friedman, Karina Yazdanbakhsh   +4 more
doaj   +1 more source

Subcutaneous immunotherapy induces alterations in monocytes and dendritic cells homeostasis in allergic rhinitis patients

Allergy, Asthma & Clinical Immunology, 2018
Background Specific subcutaneous immunotherapy (SCIT) can achieve long-term remission in patients with allergic rhinitis (AR) through complex and still unknown mechanisms.
Letícia Sousa, Carmen Martín-Sierra, Celso Pereira, Graça Loureiro, Beatriz Tavares, Susana Pedreiro, António Martinho, Artur Paiva   +7 more
doaj   +1 more source

Intestinal blood flow in patients with chronic heart failure: A link with bacterial growth, gastrointestinal symptoms, and cachexia [PDF]

, 2014
Background: Blood flow in the intestinal arteries is reduced in patients with stable heart failure (HF) and relates to gastrointestinal (GI) symptoms and cardiac cachexia.
Alastair Watson, Alexander Swidsinski, Anja Sandek, Anke Grosse-Herrenthey, Anker, Arslan, Boyd, Dimenas, Eriksen, Evans, Farkas, Fraquelli, Genth-Zotz, Gutierrez, Jougasaki, Juergen Bauditz, Kleessen, Larissa Cramer, Maisel, Mathias Rauchhaus, Maynard, Miroslava Valentova, Monika Krueger, Nadja Scherbakov, Peschel, Ralph Herrmann, Sandek, Sandek, Schroedl, Sim, Stefan D. Anker, Stephan von Haehling, Svedlund, Swedberg, Takala, Von Haehling, Wieland Schroedl, Wolfram Doehner   +37 more
core   +1 more source

Topical Menthol, Ice, Peripheral Blood Flow, and Perceived Discomfort [PDF]

, 2013
Context : Injury management commonly includes decreasing arterial blood flow to the affected site in an attempt to reduce microvascular blood flow and edema and limit the induction of inflammation.
Jacks, Dean E., Ledford, Elizabeth R., Topp, Robert V.   +2 more
core   +2 more sources

A model for upstream signalling in the control of capillary blood flow

Journal of Medical and Scientific Research, 2023
Blood supply to tissues is controlled through vasoconstriction and vasodilation activated by components of the vascular wall and smooth muscle cells.
David Townsend
doaj   +1 more source

Cerebral blood flow predicts differential neurotransmitter activity [PDF]

, 2018
Application of metabolic magnetic resonance imaging measures such as cerebral blood flow in translational medicine is limited by the unknown link of observed alterations to specific neurophysiological processes. In particular, the sensitivity of cerebral
Bertolino, A, Boak, L, Brown, G, Chatham, C, Dukart, J, Forsyth, A, Hawkins, P, Hipp, J, Holiga, Š, Honey, GD, Lingford-Hughes, AR, Liu, T, McMillan, R, Mehta, MA, Merlo-Pich, E, Muthukumaraswamy, S, Myers, J, Nutt, DJ, Paulus, M, Risterucci, C, Sambataro, F, Schobel, S, Umbricht, D, Williams, SC, Zelaya, FO   +24 more
core   +6 more sources

Blood Rheology: Key Parameters, Impact on Blood Flow, Role in Sickle Cell Disease and Effects of Exercise

Frontiers in Physiology, 2019
Blood viscosity is an important determinant of local flow characteristics, which exhibits shear thinning behavior: it decreases exponentially with increasing shear rates. Both hematocrit and plasma viscosity influence blood viscosity.
E. Nader, Sarah C. Skinner, M. Romana, R. Fort, Nathalie Lemonne, N. Guillot, A. Gauthier, S. Antoine-Jonville, C. Renoux, M. Hardy-Dessources, E. Stauffer, P. Joly, Y. Bertrand, P. Connes   +13 more
semanticscholar   +1 more source

Blood flow and microgravity

Comptes Rendus. Mécanique, 2016
AbstractThe absence of gravity during space flight can alter cardio-vascular functions partially due to reduced physical activity. This affects the overall hemodynamics, and in particular the level of shear stresses to which blood vessels are submitted.
Lionel Bureau, Lionel Bureau, Frank Dubois, Chaouqi Misbah, Chaouqi Misbah, Thomas Podgorski, Thomas Podgorski, Daria Tsvirkun, Alain Duperray, Alain Duperray, Christophe Minetti, Alexander Farutin, Alexander Farutin, Gwennou Coupier, Gwennou Coupier, Mikhail Vysokikh   +15 more
openaire   +4 more sources

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models

Nature Neuroscience, 2018
Cerebral blood flow (CBF) reductions in Alzheimer’s disease patients and related mouse models have been recognized for decades, but the underlying mechanisms and resulting consequences for Alzheimer’s disease pathogenesis remain poorly understood. In APP/
J. C. Cruz Hernández, O. Bracko, Calvin J. Kersbergen, V. Muse, Mohammad Haft-Javaherian, Maxime Berg, Laibaik Park, Lindsay K. Vinarcsik, I. Ivasyk, Daniel A. Rivera, Y. Kang, Marta Cortes-Canteli, Myriam Peyrounette, Vincent Doyeux, Amy Smith, Joan Zhou, G. Otte, Jeffrey D. Beverly, Elizabeth Davenport, Y. Davit, Charles P. Lin, S. Strickland, C. Iadecola, S. Lorthois, N. Nishimura, C. Schaffer   +25 more
semanticscholar   +1 more source

Silent infarcts in sickle cell disease occur in the border zone region and are associated with low cerebral blood flow.

Blood, 2018
Silent cerebral infarcts (SCIs) are associated with cognitive impairment in sickle cell anemia (SCA). SCI risk factors include low hemoglobin and elevated systolic blood pressure; however, mechanisms underlying their development are unclear.
A. Ford, D. Ragan, S. Fellah, M. Binkley, M. Fields, K. Guilliams, H. An, L. Jordan, R. McKinstry, Jin-Moo Lee, M. DeBaun   +10 more
semanticscholar   +1 more source