Results 41 to 50 of about 11,049,702 (406)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Galectin-1 is associated with hematopoietic cell engraftment in murine MHC-mismatched allotransplantation

Frontiers in Immunology
Haploidentical hematopoietic cell transplantation (haplo-HCT) is associated with an increased risk of allograft rejection. Here, we employed a major histocompatibility complex (MHC)-mismatched allogeneic HCT (allo-HCT) murine model to better understand ...
Ahmad Shaikh, Ahmad Shaikh, Ahmad Shaikh, Arunakumar Gangaplara, Arunakumar Gangaplara, Abdoul Kone, Katherine Almengo, Mariama D. Kabore, Mohamed A.E. Ali, Xin Xu, Ankit Saxena, Maria Lopez-Ocasio, J. Philip McCoy, Courtney D. Fitzhugh   +13 more
doaj   +1 more source

Comparison of the Effects of Ice and 3.5% Menthol Gel on Blood Flow and Muscle Strength of the Lower Arm [PDF]

, 2011
Context: Soft-tissue injuries are commonly treated with ice or menthol gels. Few studies have compared the effects of these treatments on blood flow and muscle strength.
Jacks, Dean E, Kaufmann, Jeremiah S., Mink, Amber M., Topp, Robert V, Winchester, Lee J   +4 more
core   +1 more source

Skin blood flow changes during apneic spells in preterm infants [PDF]

, 1989
Changes in skin blood flow during apneic spells were determined in 18 preterm infants using a diode laser Doppler flow meter without light conducting fibres.
Aarnoudse, J.G., Greve, J., Jentink, H.W., Mul, F.F.M. de, Okken, A., Suichies, H.E.   +5 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Regulation of Coronary Blood Flow.

Comprehensive Physiology, 2017
The heart is uniquely responsible for providing its own blood supply through the coronary circulation. Regulation of coronary blood flow is quite complex and, after over 100 years of dedicated research, is understood to be dictated through multiple ...
Adam G. Goodwill, G. Dick, Alexander M. Kiel, J. Tune   +3 more
semanticscholar   +1 more source

Mesenteric Vascular Dysregulation and Intestinal Inflammation Accompanies Experimental Spinal Cord Injury

, 2016
Cervical and high thoracic spinal cord injury (SCI) drastically impairs autonomic nervous system function. Individuals with SCI at thoracic spinal-level 5 (T5) or higher often present cardiovascular disorders that include resting systemic arterial ...
Besecker, Emily Swartz, Cooper, Timothy K., Deiter, Gina M., Holmes, Gregory Michael, Pironi, Nicole   +4 more
core   +1 more source

High-density speckle contrast optical tomography (SCOT) for three dimensional tomographic imaging of the small animal brain [PDF]

, 2017
High-density speckle contrast optical tomography (SCOT) utilizing tens of thousands of source-detector pairs, was developed for in vivo imaging of blood flow in small animals.
Culver, Joseph P, Dragojevic, Tanja, Durduran, Turgut, Hollmann, Joseph L, Justicia, Carles, Valdes, Claudia P, Varma, Hari M   +6 more
core   +3 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation

Haematologica, 2016
Iron overload results in significant morbidity and mortality in β-thalassemic patients. Insufficient hepcidin is implicated in parenchymal iron overload in β-thalassemia and approaches to increase hepcidin have therapeutic potential.
Huiyong Chen, Tenzin Choesang, Huihui Li, Shuming Sun, Petra Pham, Weili Bao, Maria Feola, Mark Westerman, Guiyuan Li, Antonia Follenzi, Lionel Blanc, Stefano Rivella, Robert E. Fleming, Yelena Z. Ginzburg   +13 more
doaj   +1 more source