Results 91 to 100 of about 6,138,867 (237)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Application progress of blood flow restriction training in patients with cardiovascular diseases

Huli yanjiu
This article reviewed the efficacy and mechanisms of blood flow restriction training,application protocol, parameter adjustment,and safety of blood flow restriction training in patients with cardiovascular diseases.The aim is to provide reference for ...
YANG Yi, ZHANG Rui, JIN Ming, CEN Mei
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Efeito de quatro semanas de treinamento sobre os índices de aptidão aeróbia e força muscular: influência da intensidade e da oclusão de fluxo sanguíneo [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2014.O objetivo deste estudo foi analisar e comparar os efeitos de quatro diferentes tipos de treinamento aeróbio
Oliveira, Mariana Fernandes Mendes de
core  

Table_1_Chronic Blood Flow Restriction Exercise Improves Objective Physical Function: A Systematic Review.DOCX

, 2019
Background: Blood flow restriction or KAATSU exercise training is associated with greater muscle mass and strength increases than non-blood flow restriction equivalent exercise.
Anthony K. May (7292726), Stuart A. Warmington (7292729), Matthew J. Clarkson (7292723)   +2 more
core   +1 more source

The impact of acute blood‐flow‐restriction resistance exercise on somatosensory‐evoked potentials in healthy adults

Experimental Physiology
Blood‐flow‐restriction exercise (BFREX) is an emerging method to stimulate hypertrophy and strength without the need for high training loads. However, the impact of BFREX concerning somatosensory processing remains elusive.
Tom Maudrich, Sebastian Degener, Patrick Ragert, Rouven Kenville   +3 more
doaj   +1 more source

Comparison of blood flow restriction and resistance trainings with medium intensity on salivary cortisol and alpha-amylase levels of beginner female body builders

Fiyz̤, 2020
Background: Various exercise trainings affect human’s hormones. This study aimed to compare the effect of blood flow restriction (BFR) and resistance trainings with medium intensity (Kaatsu training) on salivary cortisol and alpha-amylase levels of ...
Mir-Jafari SM , Shabani R
doaj  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Table_2_Chronic Blood Flow Restriction Exercise Improves Objective Physical Function: A Systematic Review.DOC

, 2019
Background: Blood flow restriction or KAATSU exercise training is associated with greater muscle mass and strength increases than non-blood flow restriction equivalent exercise.
Anthony K. May (7292726), Stuart A. Warmington (7292729), Matthew J. Clarkson (7292723)   +2 more
core   +1 more source