Advanced Science, EarlyView.A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Heechang Moon +12 more
wiley +1 more source
Drug Repurposing for Treating NCOR‐Related Intellectual Disability
Advanced Science, EarlyView.An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong +15 more
wiley +1 more source
Chaos based blood glucose noninvasive measurement: new concept and custom study
BIO Web of Conferences, 2017 Background. Non invasive monitoring of Blood Glucose (BG) has been a challenge calling for new accurate and fast measurement methods. Objective. To propose new concept of chaos based BG non invasive test aiming at personal customization requirements ...
Cui Li +3 more
doaj +1 more source
Potential Cost Savings for the Healthcare System of the Russian Federation Through the Utilization of a Blood Glucose Meter With Color Range Indicator. [PDF]
J Diabetes Sci Technol, 2021 Agnah J +8 more
europepmc +1 more source
Advanced Science, EarlyView.Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang +13 more
wiley +1 more source
Healthcare Professional Perceptions of Blood Glucose Meter Features That Support Achievement of Self-Management Goals Recommended by Clinical Practice Guidelines. [PDF]
J Diabetes Sci Technol, 2021 Greenwood DA, Grady M.
europepmc +1 more source
Advanced Science, EarlyView.Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji +11 more
wiley +1 more source
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Design of the DAVOS Study: Diabetes Smartphone App, a Fully Automatic Transmission of Data From the Blood Glucose Meter and Insulin Pens Using Wireless Technology to Enhance Diabetes Self-Management-A Study Protocol for a Randomized Controlled Trial. [PDF]
J Diabetes Sci Technol, 2023 Grosser F +6 more
europepmc +1 more source
The Accuracy of Different Blood Glucose Meters in Relation to the True Blood Glucose Level
, 2019 Around 371 million people have diabetes worldwide, meaning that diabetes has reached epidemic proportions. Diabetics, who either have trouble or cannot produce a blood glucose regulating hormone called insulin, check their blood sugars on devices called
Huddlestun, Asher
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