Results 111 to 120 of about 3,019,588 (285)

3D Bioprinted Blood–Brain–Tumor Barrier Spheroid‐Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS‐Producing Ruthenium as a Potential Therapeutic Candidate

Advanced Science, EarlyView.
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee, Chan Ho Jeon, Doyun Kim, Minjae Lee, Minji Kwon, Joon Myong Song   +5 more
wiley   +1 more source

Multi-user Glucose Meter with Insulin Dosage Recommendation [PDF]

, 2018
Diabetes (Diabetes mellitus) is a metabolic disease that occurs either when the pancreas does not produce enough insulin to regulate blood sugar or when the body itself cannot effectively use the insulin it produces, it leads to increased concentration ...
Sauli, Zaliman; School of Microelectronic Engineering, Universiti Malaysia Perlis, Pauh Putra Campus, 02600 Arau, Perlis, Malaysia, Chung, Wen Yaw; Chung Yuan Christian University, Taiwan., Paglinawan, Arnold C.; School of Electrical, Electronics and Computer Engineering, Mapua University, 658 Muralla St., Intramuros, Manila, Philippines 1002, Cruz, Febus Reidj; School of Electrical, Electronics and Computer Engineering, Mapua University, 658 Muralla St., Intramuros, Manila, Philippines 1002, Paglinawan, Charmaine; School of Electrical, Electronics and Computer Engineering, Mapua University, 658 Muralla St., Intramuros, Manila, Philippines 1002, Blas, Dorothy Faye; School of Electrical, Electronics and Computer Engineering, Mapua University, 658 Muralla St., Intramuros, Manila, Philippines 1002, Felix, Almie Anne; School of Electrical, Electronics and Computer Engineering, Mapua University, 658 Muralla St., Intramuros, Manila, Philippines 1002, Daza, John Colin; School of Electrical, Electronics and Computer Engineering, Mapua University, 658 Muralla St., Intramuros, Manila, Philippines 1002   +7 more
core  

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

Self-monitoring of blood glucose is an important component of effective diabetes mellitus control

Клинический разбор в общей медицине
Diabetes mellitus (DM) falls into the category of socially significant non-communicable diseases. When ineffectively treated, DM can considerably worsen the patients’ quality of life due to the development of systemic vascular complications leading to ...
Elena V. Biryukova, Inna V. Solovyova, Inna V. Solovyova   +2 more
doaj   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

User-centred concept design of a blood glucose meter [PDF]

, 2014
Tyypin 1 diabetesta sairastavan henkilön sitoutuminen tiheään päivittäiseen verensokeripitoisuuden omaseurantaan on avainasemassa sairauden menestyksekkäälle hallinnalle.
Berg, Emilia
core   +1 more source

Agreement of a Handheld Glucose Meter with Laboratory Serum Glucose Measurements in Dairy Cows

Dairy
Blood glucose concentration is commonly used to assess energy metabolism in dairy cows. Handheld glucose meters allow rapid measurement under farm conditions, but their performance in cattle may differ from that obtained with laboratory methods.
Dovilė Malašauskienė, Mindaugas Televičius, Gabija Lembovičiūtė, Greta Šertvytytė, Samanta Grigė, Akvilė Girdauskaitė, Melanie Christina Siebert, Vita Riškevičienė, Geert R. G. Opsomer, Priit Karis, Ramūnas Antanaitis   +10 more
doaj   +1 more source

Habitat‐Specific Design Strategies for Untethered Soft Robots

Advanced Science, EarlyView.
Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li, Zhikun Miao, Tuck‐Whye Wong, Tiefeng Li   +3 more
wiley   +1 more source

Clinical Characteristics and Glucose Monitoring Satisfaction Associated With Blood Glucose Meter Featuring Color Range Indicator in Patients With Type 2 Diabetes. [PDF]

J Diabetes Sci Technol, 2021
Al Hayek A, Alwin Robert A, Al Dawish M.
europepmc   +1 more source

Targeting Cannabinoid 1 Receptor in Macrophages Alleviates Psoriatic Skin Inflammation Through the AUF1–NLRP3 Axis

Advanced Science, EarlyView.
Macrophage CB1R emerges as a key driver of psoriatic inflammation by suppressing AUF1‐mediated post‐transcriptional control of NLRP3. CB1R inhibition restores AUF1‐dependent NLRP3 mRNA decay, restrains inflammasome activation, and alleviates psoriasis‐like inflammation.
Hongseo Choi, Sukyoung Han, Jinho Kim, Ji Hye Han, Eunsu Kim, Yeonjeong Heo, Minju Lee, Jooyoung Lee, Heerim You, Soyoun Lee, Su‐Hee Han, Ilrok Yoon, Sung Anjeon, Hyerim Kang, Seungyeon Ryu, Hyun‐Ji Park, Eunha Kim, Chul Hwan Bang, Ji Hyun Lee, Josephine M. Egan, Jung‐Woong Kim, Eun Kyung Lee, Wook Kim   +22 more
wiley   +1 more source