Results 101 to 110 of about 18,209,937 (340)

Blood Group Discrepancy in a Donor Due to a Rare Ax/Aweak Subgroup Phenotype with ABO*AW.31.01/*O.01.75 Genotype

open access: yesGlobal Journal of Transfusion Medicine
The most crucial blood group system in transfusion medicine is still the ABO system. Any unresolved discrepancy could result in the patient receiving blood that is incompatible and could trigger acute intravascular hemolysis. ABO subgroups are one of the
Sneha Samir Babaria   +2 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Association between COVID-19 Infection and ABO Blood Types in Mazandaran Province, Iran: A Cross-Sectional Study

open access: yesJournal of Mazandaran University of Medical Sciences, 2021
Background and purpose: The association between ABO blood types and Coronavirus disease 2019 (COVID-19) have been investigated in several studies but there are inconsistencies in results.
Hamed Rouhanizadeh   +15 more
doaj  

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Multimodal Biometric Analysis: Exploring Lip Print, Fingerprint, and Blood Group Correlations in the Firozabad Populations

open access: yesJournal of Forensic Science and Medicine
Aim: This study aimed to establish a relationship between blood groups, fingerprint types, and lip prints that can be utilized to distinguish between genders when identifying a person.
Shailja Singh   +6 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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