Results 281 to 290 of about 500,318 (318)
Advanced Science, EarlyView.This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare +7 more
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HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury
Advanced Science, EarlyView.Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou +7 more
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Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
Advanced Science, EarlyView.Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen +9 more
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Blood Group Antigens: Blood Group Carbohydrate Antigens [PDF]
, 2009 The most popular blood group antigen system, ABO antigens had been known to consist of alpha1,2-fucosylated galactose substituted with alpha1,3-N-acetylgalactosamine (A) or galactose (B). These biochemical results were clearly confirmed and further investigated by the molecular cloning of blood group A synthase cDNA (Yamamoto et al. 1990a, 1990b).
Koichi Iwamura +2 more
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The Rare Blood Group Antigen, Wu
Vox Sanguinis, 1976Abstract. The inheritance of the Wu antigen in three families is described. The observations suggest that the antigen is inherited as a Mendelian dominant character. Wu segregates independently of sex and of the ABO, MNSs, Rh, Lutheran, Duffy and Kidd blood group systems. Independence of Kell is also quite likely. Wu is a very rare antigen.
P. Howell +4 more
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A New Blood Group Antigen, Hov
Vox Sanguinis, 1973Abstract. A new blood group antigen, Hov, is described. The antigen is not closely linked to the MNSs, P, Rhesus secretor, Duffy and Kidd loci, and it is not X‐linked. 1,155 blood samples were tested; two of these had the new antigen.
Agnes Szaloky +2 more
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Nomenclature of Blood Group Antigens [PDF]
, 1995 “The term antigen is used in two senses, the first to describe a molecule which generates an immune response and the second a molecule which reacts with anti- bodies or primed T-cells irrespective of its ability to generate them” (Roitt, 1991).
Philippe Rouger, Pierre-Yves Le Pennec
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ABO blood groups and Australia antigen
Clinical Genetics, 1974The distribution of ABO blood in two groups of people with Australia antigen was studied (121 blood donors and 128 patients) and in 3,091 controls was investigated. There was a significant excess of A in comparison with o when the two groups were combined, and when the two groups were tested for (A + B): (AB +O) individually and together, both were ...
R. Ananthakrishnan +2 more
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The Blood Group Antigen Mia in Japanese [PDF]
Vox Sanguinis, 1963 SummaryThe blood group antigen Mia was found in one of 3,350 randomly selected Japanese. In the family of the propositus, it could be shown that the Mia gene was traveling on an Ms chromosome. The simultaneous occurrence of the two rare genes Mia and Dia in this family has established the lack of genetic relationship between them.
S. Masaki +4 more
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