Results 31 to 40 of about 11,805,552 (254)

In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures

Frontiers in Chemistry, 2022
Glycosylation of viral envelope proteins is important for infectivity and immune evasion. The SARS-CoV-2 spike protein is heavily glycosylated and host-derived glycan modifications contribute to the formation of specific immunogenic epitopes, enhance the
Julia König-Beihammer, Ulrike Vavra, Yun-Ji Shin, Christiane Veit, Clemens Grünwald-Gruber, Yasmin Gillitschka, Jasmin Huber, Manuela Hofner, Klemens Vierlinger, Dieter Mitteregger, Andreas Weinhäusel, Richard Strasser   +11 more
doaj   +1 more source

Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. [PDF]

, 2008
BACKGROUND: The asexual blood stages of the human malaria parasite Plasmodium falciparum produce highly immunogenic polymorphic antigens that are expressed on the surface of the host cell.
Christopher J. Drakeley, Saeed Maha, Saeed, Maha, Alexander Neal, Saeed, M., Geoffrey A T Targett, Sutherland, Colin J, Drakeley Christopher J., Targett Geoffrey A. T., Roeffen Will, Geoffrey A. T. Targett, Colin J. Sutherland, Targett, Geoffrey AT, Alexander, N., Neal Alexander, Colin J Sutherland, Sutherland Colin J., Targett, G.A.T., Roeffen, W.F.G., Roeffen, Will, Maha Saeed, Alexander, Neal, Drakeley, Christopher J, Drakeley, C., Will Roeffen, Christopher J Drakeley, Sutherland, C.J.   +26 more
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

A deep learning approach to prediction of blood group antigens from genomic data [PDF]

BACKGROUND: Deep learning methods are revolutionizing natural science. In this study, we aim to apply such techniques to develop blood type prediction models based on cheap to analyze and easily scalable screening array genotyping platforms.METHODS ...
Ritari, Jarmo, Ostrowski, Sisse R., Hyvärinen, Kati, Pedersen, Ole B., Sækmose, Susanne, Erikstrup, Christian, Brodersen, Thorsten, Bay, Jakob T., Bruun, Mie T., Olsson, Martin L., Larsen, Rune, Didriksen, Maria, Partanen, Jukka, Ullum, Henrik, Moslemi, Camous, Nielsen, Kaspar R., Dinh, Khoa M., Dowsett, Joseph, Mikkelsen, Christina, Saekmose, Susanne, Didriksen, Maria,, Bruun, Mie T.,, Larsen, Rune,, Ostrowski, Sisse R.,, Hyvärinen, Kati,, Moslemi, Camous,, Dowsett, Joseph,, Pedersen, Ole B.,, Brodersen, Thorsten,, Ritari, Jarmo,, Ullum, Henrik,, Partanen, Jukka,, Dinh, Khoa M.,, Bay, Jakob T.,, Olsson, Martin L.,, Mikkelsen, Christina,, Nielsen, Kaspar R.,, Erikstrup, Christian,, Sækmose, Susanne,, Lund University.   +39 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phenotypic Frequency of Clinically Significant Blood Group Antigens (Rh, Kell, Kidd, and Duffy) in Blood Donors of the Blood Center at a Tertiary Care Referral Teaching Hospital in Tirupati, Andhra Pradesh, South India

Global Journal of Transfusion Medicine
Background and Objectives: The knowledge of various blood group antigen and phenotype frequencies in a population is important in selecting compatible blood in alloimmunized patients. Such information in Indian population is very limited.
K. V. Sreedhar Babu, M. D. Praveen, B. Suresh Babu   +2 more
doaj   +1 more source

Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection

Viruses, 2019
Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín, Susana Vila-Vicent, Noelia Carmona-Vicente, Cristina Santiso-Bellón, Jesús Rodríguez-Díaz, Javier Buesa   +5 more
doaj   +1 more source

Blood typing of feline AB blood group antigens in a random population.

, 2016
Blood typing of feline AB blood group antigens in a random population.
Shigenori Ikemoto (3226944), Chihiro Udagawa (3226941), Shota Nakazawa (3226932), Kazuhiko Ochiai (128430), Toshinori Sako (3226950), Azusa Gin (3226920), Toshihiko Tsutsui (3226911), Naomi Tada (3226914), Atsushi Sakamoto (695822), Toshinori Omi (430385), Makoto Bonkobara (3226917), Hitomi Oda (3226926), Kyoichi Tamura (3226929), Hiroko Mitsui (3226938), Yong Hwa Chong (3226923), Shuichi Tsuchida (430384), Yuiko Kato (3226947), Daigo Azakami (3226935), Takeshi Inagaki (3226908)   +18 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Red blood cell microparticles and blood group antigens: an analysis by flow cytometry.

, 2012
BACKGROUND: The storage of blood induces the formation of erythrocytes-derived microparticles. Their pathogenic role in blood transfusion is not known so far, especially the risk to trigger alloantibody production in the recipient.
Rubin, O., Delobel, J., Lion, N., Crettaz, D., Canellini, G., Tissot, J.D.   +5 more
core   +1 more source