Results 41 to 50 of about 11,805,552 (254)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Extended phenotyping of blood group antigens: Towards improved transfusion practices

Global Journal of Transfusion Medicine, 2020
Even though the International Society of Blood Transfusion has defined 38 blood group systems, only ABO and RhD are matched while selecting a compatible unit for blood recipients of Indian origin.
Swati Kulkarni, Harita Maru
doaj   +1 more source

Distribution of ABO and Rh-Hr blood group antigens, alleles and haplotypes in the mountain region of Ajara (Georgia) [PDF]

, 2013
ABO and Rh-Hr blood group antigens represent a genetically stably determined trait with many-sided biological and clinical significance. The indigenous Ajarian population (105 subjects) was investigated for ABO Rh-Hr red cell blood group antigens.
Nagervadze, M, Diasamidze, A, Dumbadze, G, Tckvitinidze, S, Koridze, M, Khukhunaishvili, R, Akhvlediani, L   +6 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Clinically significant minor blood group antigens amongst South Indian donor population

IMC Journal of Medical Science, 2023
Background and objectives: Distribution of blood group antigen varies among different races. It is important to know the distribution of these antigens so as to provide a donor database that aid in providing compatible blood units for patients with ...
Soonam John, Archana Kuruvanplackal Achankunju, Madathingal Sugathan Suma, Sasikala Nadanganan   +3 more
doaj   +1 more source

Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific.

, 2008
Naturally acquired antibody responses provide partial protection from clinical malaria, and blood-stage parasite vaccines under development aim to prime such responses. To investigate the determinants of antibody response longevity, immunoglobulin G (IgG)
Conway, David J, Samuel Dunyo, Tetteh, Kevin KA, Dunyo, Samuel, Lanar, David E, Akpogheneta, Onome J, Margaret Pinder, Duah, Nancy O, Pinder, Margaret, David E. Lanar, David J. Conway, Onome J. Akpogheneta, Nancy O. Duah, Kevin K. A. Tetteh   +13 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Blood group and Rhesus antigens among Blood donors attending the Central Blood Bank, Sudan [PDF]

, 2013
Background: It is well known that the Rhesus system remains the second most clinically important blood group system after the ABO. There is no published work regarding the frequency of various Rhesus antigens among Sudanese population.Objectives: In ...
Hussien, SM, Shahata, WM, Adam, I, Abass, A-E, Khalil, HB   +4 more
core   +1 more source

The potential role of antibodies against minor blood group antigens in renal transplantation [PDF]

, 2020
Blood group antigens are red blood cell (RBC) surface markers comprising specific carbohydrate moieties attached to the glycolipids and glycoproteins within the membrane.
Kotagiri, P, Masterson, R, Hughes, P, Hogan, C, Holt, SG   +4 more
core   +1 more source