Results 21 to 30 of about 328,824 (265)

In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures

Frontiers in Chemistry, 2022
Glycosylation of viral envelope proteins is important for infectivity and immune evasion. The SARS-CoV-2 spike protein is heavily glycosylated and host-derived glycan modifications contribute to the formation of specific immunogenic epitopes, enhance the
Julia König-Beihammer, Ulrike Vavra, Yun-Ji Shin, Christiane Veit, Clemens Grünwald-Gruber, Yasmin Gillitschka, Jasmin Huber, Manuela Hofner, Klemens Vierlinger, Dieter Mitteregger, Andreas Weinhäusel, Richard Strasser   +11 more
doaj   +1 more source

Extended phenotyping of blood group antigens: Towards improved transfusion practices

Global Journal of Transfusion Medicine, 2020
Even though the International Society of Blood Transfusion has defined 38 blood group systems, only ABO and RhD are matched while selecting a compatible unit for blood recipients of Indian origin.
Swati Kulkarni, Harita Maru
doaj   +1 more source

Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection

Viruses, 2019
Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín, Susana Vila-Vicent, Noelia Carmona-Vicente, Cristina Santiso-Bellón, Jesús Rodríguez-Díaz, Javier Buesa   +5 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Phenotypic Frequency of Clinically Significant Blood Group Antigens (Rh, Kell, Kidd, and Duffy) in Blood Donors of the Blood Center at a Tertiary Care Referral Teaching Hospital in Tirupati, Andhra Pradesh, South India

Global Journal of Transfusion Medicine
Background and Objectives: The knowledge of various blood group antigen and phenotype frequencies in a population is important in selecting compatible blood in alloimmunized patients. Such information in Indian population is very limited.
K. V. Sreedhar Babu, M. D. Praveen, B. Suresh Babu   +2 more
doaj   +1 more source

Group antigens of various animals

RUDN Journal of Agronomy and Animal Industries, 2015
In many animals on the erythrocytes are present group antigens similar to the antigens of the system AB0 human. Immunogenetic features of blood does not change throughout the life of the animal. Primates have different combinations of blood group 0, А, В
E A Ryskina, F N Gilmiyarova
doaj   +1 more source

Clinically significant minor blood group antigens amongst South Indian donor population

IMC Journal of Medical Science, 2023
Background and objectives: Distribution of blood group antigen varies among different races. It is important to know the distribution of these antigens so as to provide a donor database that aid in providing compatible blood units for patients with ...
Soonam John, Archana Kuruvanplackal Achankunju, Madathingal Sugathan Suma, Sasikala Nadanganan   +3 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source