Results 61 to 70 of about 4,588,550 (363)
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Objectives: the aim is to estimate the share of people with AH among the Tubalars and nonindigenous inhabitants of the Altai Republic taking into account a sex, an ethnic origin and to analyze genetic predisposition to the diseases of АВ0, Rh, MN, P ...
M U Ogargov+4 more
doaj
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Could the ABO Blood Group Types be Associated with COVID-19 Mortality?
Aim:Currently, it is still a matter of debate whether a particular blood types is associated with an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Sema Alacam, Nagehan Didem Sari
doaj +1 more source
Sanguine: Visual Analysis for Patient Blood Management [PDF]
Blood transfusion is a frequently performed medical procedure in surgical and nonsurgical contexts. Although it is frequently necessary or even life-saving, it has been identified as one of the most overused procedures in hospitals. Unnecessary transfusions not only waste resources but can also be detrimental to patient outcomes.
arxiv +1 more source
Genetic Analysis of ABO and Rh Blood Groups in Brahmin Population of Uttar Pradesh, India” [PDF]
A series of glycoprotein and glycolipids on the red blood cell surface constitute blood group antigens. These are A, B, AB and O in ABO blood group system and Rh in rhesus blood group system. These antigens are genetically controlled.
Vandana V. Rai
core +1 more source
Blood pressure control by home monitoring : meta-analysis of randomised trials [PDF]
Objective To determine the effect of home blood pressure monitoring on blood pressure levels and proportion of people with essential hypertension achieving targets. Design Meta-analysis of 18 randomised controlled trials.
Cappuccio, Francesco+3 more
core +2 more sources
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek+15 more
wiley +1 more source
Aim:To investigate if there is an association between the blood groups of convalescent plasma (CP) donors and Severe acute respiratory syndrome Coronavirus-2 infection risk.Methods:Blood groups of 30605 CP donors were compared with 1316676 Turkish Red ...
Mustafa Yilmaz+7 more
doaj +1 more source