Results 141 to 150 of about 2,868,834 (341)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Blood Lead Level and Renal Impairment among Adults: A Meta-Analysis. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Kuraeiad S, Kotepui M.
europepmc   +1 more source

Применение интестинальной подслизистой оболочки для инкапсуляции островков поджелудочной железы при ксенотрансплантации [PDF]

open access: yes, 2009
Dynamics of glucose blood level changes after xenotransplantation of pancreatic islets incapsulated into small intestinal submucosa (SIS) was investigated in rabbits with experimental type 1 diabetes mellitus.
Bozhok, G.A.   +7 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Modeling of Blood Lead Levels in Astronauts Exposed to Lead from Microgravity-Accelerated Bone Loss [PDF]

open access: yes
Human exposure to lead has been associated with toxicity to multiple organ systems. Studies of various population groups with relatively low blood lead concentrations (
Garcia, H., James, J., Tsuji, J.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Blood Lead Level of Workers in a Printing Industry

open access: yesArchives of Occupational Health, 2019
Background: Different chemical materials especially inks are used in printing industry and lead is one of the ingredients that make up its pigments.
Zhaleh Sedghi Noushabadi   +3 more
doaj  

Blood Lead Level Is Negatively Associated With Bone Mineral Density in U.S. Children and Adolescents Aged 8-19 Years. [PDF]

open access: yesFront Endocrinol (Lausanne), 2022
Cui A   +7 more
europepmc   +1 more source

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