Results 121 to 130 of about 1,492,573 (300)

Stability Of Blood Lead Levels In Children With Chronic Low-Level Lead Absorption

open access: yes, 2021
Background and Significance: Despite the many historical efforts by the U.S. to reduce lead (Pb) in the environment, childhood Pb poisoning continues to be a public health issue today.
Del Rio, Michelle
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Lead Poisoning and The Bell Curve

open access: yes
A robust environmental health literature demonstrates that preschool lead exposure can cause neurodevelopmental damage and associated adverse impacts on IQ, education, and behavior.
Nevin, Rick
core  

Beta-Adrenergic Receptor Density and Adenylate Cyclase Activity in Lead- Exposed Rat Brain after Cessation of Lead Exposure

open access: yes, 2008
To understanding the reversible or irreversible harm to the beta- adrenergic system in the brain of lead-exposed rats, this study sets up an animal model to estimate the change in the sympathetic nervous system of brain after lead exposure was withdrawn.
CHANG, HUOY-ROU;TSAO, DER-AN;YU, HSIN- SU;HO, CHI-KUNG   +1 more
core  

Blood Lead Level and Renal Impairment among Adults: A Meta-Analysis. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Kuraeiad S, Kotepui M.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Monetary benefits of preventing childhood lead poisoning with lead-safe window replacement

open access: yes
Previous estimates of childhood lead poisoning prevention benefits have quantified the present value of some health benefits, but not the costs of lead paint hazard control or the benefits associated with housing and energy markets. Because older housing
Berg, Michael   +3 more
core  

Blood Lead Level of Workers in a Printing Industry

open access: yesArchives of Occupational Health, 2019
Background: Different chemical materials especially inks are used in printing industry and lead is one of the ingredients that make up its pigments.
Zhaleh Sedghi Noushabadi   +3 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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