Results 1 to 10 of about 5,484,454 (382)
Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids [PDF]
Nature, 2010 Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic ...Tanya M. Teslovich, K. Musunuru, A. Smith, Andrew C. Edmondson, I. Stylianou, M. Koseki, J. Pirruccello, S. Ripatti, D. Chasman, C. Willer, C. T. Johansen, S. Fouchier, A. Isaacs, G. Peloso, M. Barbalić, S. Ricketts, J. Bis, Y. Aulchenko, G. Thorleifsson, M. Feitosa, J. Chambers, M. Orho-Melander, O. Melander, T. Johnson, Xiaohui Li, Xiuqing Guo, Mingyao Li, Y. Cho, M. Go, Y. J. Kim, Jong-Young Lee, T. Park, Kyungeun Kim, X. Sim, R. Ong, Damien C. Croteau-Chonka, L. Lange, Joshua D. Smith, Kijoung Song, J. Zhao, Xin Yuan, J. Luan, C. Lamina, A. Ziegler, Weihua Zhang, R. Zee, A. Wright, J. Witteman, James F. Wilson, G. Willemsen, H. Wichmann, J. Whitfield, D. Waterworth, N. Wareham, G. Waeber, P. Vollenweider, B. Voight, V. Vitart, A. Uitterlinden, M. Uda, J. Tuomilehto, J. Thompson, Toshiko Tanaka, I. Surakka, H. Stringham, T. Spector, N. Soranzo, J. Smit, J. Sinisalo, K. Silander, E. Sijbrands, A. Scuteri, J. Scott, D. Schlessinger, S. Sanna, V. Salomaa, J. Saharinen, C. Sabatti, A. Ruokonen, I. Rudan, L. Rose, R. Roberts, M. Rieder, B. Psaty, P. Pramstaller, I. Pichler, M. Perola, B. Penninx, N. Pedersen, C. Pattaro, A. Parker, G. Paré, B. Oostra, C. O’Donnell, M. Nieminen, D. Nickerson, G. Montgomery, T. Meitinger, R. McPherson, M. McCarthy, W. McArdle, D. Masson, N. Martin, F. Marroni, M. Mangino, P. Magnusson, G. Lucas, R. Luben, R. Loos, Maisa Lokki, G. Lettre, C. Langenberg, L. Launer, E. Lakatta, R. Laaksonen, K. Kyvik, F. Kronenberg, I. König, K. Khaw, J. Kaprio, L. Kaplan, Å. Johansson, M. Jarvelin, A. Janssens, E. Ingelsson, W. Igl, G. K. Hovingh, J. Hottenga, A. Hofman, A. Hicks, C. Hengstenberg, I. Heid, C. Hayward, A. Havulinna, N. Hastie, T. Harris, T. Haritunians, A. Hall, U. Gyllensten, C. Guiducci, L. Groop, Elena Gonzalez, C. Gieger, N. Freimer, L. Ferrucci, J. Erdmann, P. Elliott, K. Ejebe, A. Döring, A. Dominiczak, S. Demissie, P. Deloukas, E. D. de Geus, U. de Faire, Gabriel J Crawford, F. Collins, Y. Chen, M. Caulfield, H. Campbell, N. Burtt, L. Bonnycastle, D. Boomsma, S. Boekholdt, R. Bergman, I. Barroso, S. Bandinelli, C. Ballantyne, T. Assimes, T. Quertermous, D. Altshuler, Mark Seielstad, T. Wong, E. Tai, A. Feranil, C. Kuzawa, L. Adair, H. Taylor, I. Borecki, S. Gabriel, James G. Wilson, K. Stefánsson, U. Thorsteinsdóttir, V. Gudnason, R. Krauss, K. Mohlke, J. Ordovás, P. Munroe, J. Kooner, A. Tall, R. Hegele, J. Kastelein, E. Schadt, J. Rotter, E. Boerwinkle, D. Strachan, V. Mooser, H. Hólm, M. Reilly, N. Samani, H. Schunkert, L. Cupples, M. Sandhu, P. Ridker, D. Rader, C. V. van Duijn, L. Peltonen, G. Abecasis, M. Boehnke, S. Kathiresan +208 moresemanticscholar +3 more sourcesDeep-coverage whole genome sequences and blood lipids among 16,324 individuals [PDF]
Nature Communications, 2017 Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers potential advantages for locus discovery. We perform WGS in 16,324 participants from four ancestries at mean depth >29X and analyze genotypes with four quantitative traits—P. Natarajan, G. Peloso, S. Zekavat, M. Montasser, A. Ganna, M. Chaffin, A. Khera, Wei Zhou, Jonathan M. Bloom, J. Engreitz, J. Ernst, J. O’Connell, S. Ruotsalainen, Maris Alver, A. Manichaikul, W. Johnson, James A. Perry, T. Poterba, C. Seed, I. Surakka, T. Esko, S. Ripatti, V. Salomaa, A. Correa, R. Vasan, Manolis Kellis, B. Neale, E. Lander, G. Abecasis, B. Mitchell, S. Rich, James G. Wilson, L. Cupples, J. Rotter, C. Willer, S. Kathiresan +35 moresemanticscholar +4 more sourcesThe metabolic signature of blood lipids: a causal inference study using twins [PDF]
Journal of Lipid ResearchDyslipidemia is one of the cardiometabolic risk factors that influences mortality globally. Unraveling the causality between blood lipids and metabolites and the complex networks connecting lipids, metabolites, and other cardiometabolic traits can help ...Yutong Wang, Shunkai Liu, Weihua Cao, Jun Lv, Canqing Yu, Tao Huang, Dianjianyi Sun, Chunxiao Liao, Yuanjie Pang, Zengchang Pang, Min Yu, Hua Wang, Xianping Wu, Yu Liu, Wenjing Gao, Liming Li +15 moredoaj +2 more sourcesImpact of Isotretinoin on Blood Lipids and Liver Enzymes: A Retrospective Cohort Study in Saudi Arabia [PDF]
Therapeutics and Clinical Risk ManagementAbdullah A Alrasheed,1,2 Khalid F Alsadhan,1,2 Nawaf F Alfawzan,2 Nasser M AbuDujain,2 Ali H Alnasser,3 Hisham Almousa3 1Family and Community Medicine Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2Family and Community ...Alrasheed AA, Alsadhan KF, Alfawzan NF, AbuDujain NM, Alnasser AH, Almousa H +5 moredoaj +2 more sourcesHigh-sensitivity CRP may be a marker of HDL dysfunction and remodeling in patients with acute coronary syndrome
Scientific Reports, 2021 In patients with coronary artery disease (CAD), further increasing the level of high-density lipoprotein (HDL) cholesterol (HDL-C) as an add-on to statins cannot reduce cardiovascular risk.Xiaoyu Tang, Ling Mao, Jin Chen, Tianhua Zhang, Shuwei Weng, Xin Guo, Jie Kuang, Bilian Yu, Daoquan Peng +8 moredoaj +1 more source