Results 91 to 100 of about 4,492,214 (311)

Sufficient blood, safe blood: can we have both? [PDF]

open access: yes, 2012
The decision in September 2011 in the UK to accept blood donations from non-practicing men who have sex with men (MSM) has received significant public attention.
Schüttrumpf Jörg   +14 more
core   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

The proposal to discontinue blood testing at the Munster Centre of the Irish Blood Transfusion Service Board (BTSB) - assessment by a representative regional group

open access: yes, 1998
The role of the Irish Blood Transfusion Service is crucial to the operation of our health care system. In its 1965 Establishment Order, the key functions of the BTSB are described, inter alia, as follows (a) to take over the property {including chosen ...
Irish Blood Transfusion Service (IBTS)
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Physiological Responses, Growth Rate and Blood Metabolites Under Feed Restriction and Thermal Exposure in Kids [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2014
The study was carried out to study the cumulative effect of thermal stress and feed restriction in kids. Twelve kids of Alpine x Beetle cross were divided into two groups. Group 1 served as control and group 2 was put on restricted feeding and exposed at
O.K. Hooda, R.C. Upadhyay
doaj  

Parameter Evaluation and Application Demonstration of a New Type of Blood Vacuum Tube Cap Opening and Closing Machine

open access: yesIranian Journal of Public Health, 2019
Background: We aimed to evaluate the basic performance and basic parameters of a new type of blood vacuum tube cap opening and closing machine for further application.
Rong PU   +3 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Efficacy of Probiotic Lactobacillus spp. Isolated From Healthy Korean Indigenous Calves

open access: yesVeterinary Medicine and Science
Background A healthy gut microbiota enhances immune function and reduces infection susceptibility in neonatal calves. Objectives This study evaluated the probiotic efficacy of Lactobacillus amylovorus, Lactobacillus reuteri and Lactobacillus johnsonii ...
Ji‐Yeong Ku   +8 more
doaj   +1 more source

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